The key signalling pathways and transcriptional programmes that instruct neuronal diversity
during development have largely been identified. In this Review, we discuss how this …

Endothelial dysfunction is an important risk factor for cardiovascular disease, and it
represents the initial step in the pathogenesis of atherosclerosis. Failure to protect against …

The classic view of cortical development, embodied in the radial unit hypothesis, highlights
the ventricular radial glia (vRG) scaffold as a key architectonic feature of the developing …

The neocortex exhibits a six-layered structure that is formed by radial migration of excitatory
neurons, for which the multipolar-to-bipolar transition of immature migrating multipolar …

Radial glia (RG) cells that align in parallel in the embryonic brain are found to be able to
guide the directed migration of neurons in response to brain injury. Therefore, biomaterials …

The formation of the neocortex relies on intracellular and extracellular signaling molecules
that are involved in the sequential steps of corticogenesis, ranging from the proliferation and …

Glucocorticoids (GCs) regulate distinct physiological processes in the developing fetus, in
particular accelerating organ maturation that enables the fetus to survive outside the womb …

The circumventricular organs (CVOs) are located around the brain ventricles, lack a blood-
brain barrier (BBB) and sense blood-derived molecules. This review discusses recent …

Rho family guanosine triphosphatases (GTPases) regulate cellular signaling and
cytoskeletal dynamics, playing a pivotal role in cell adhesion, migration, and cell cycle …

Cell polarity refers to the asymmetric distribution of signaling molecules, cellular organelles,
and cytoskeleton in a cell. Neural progenitors and neurons are highly polarized cells in …