Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous
group of autoimmune disorders with varying clinical manifestations, treatment responses …

Inflammatory disorders of the skeletal muscle include polymyositis (PM), dermatomyositis
(DM),(immune mediated) necrotizing myopathy (NM), overlap syndrome with myositis …

Background Treatment for autoimmune diseases such as systemic lupus erythematosus
(SLE), idiopathic inflammatory myositis, and systemic sclerosis often involves long-term …

Background Intravenous immune globulin (IVIG) for the treatment of dermatomyositis has not
been extensively evaluated. Methods We conducted a randomized, placebo-controlled trial …

Allogeneic chimeric antigen receptor (CAR)-T cells hold great promise for expanding the
accessibility of CAR-T therapy, whereas the risks of allograft rejection have hampered its …

Objective This open‐label 12‐week study was conducted to evaluate the efficacy and safety
of tofacitinib, a JAK inhibitor, in treatment‐refractory active dermatomyositis (DM). Methods …

Idiopathic inflammatory myopathies (IIM) are a heterogenous family of diseases that can
affect the muscles, skin, lungs, and joints. There have been prior attempts to classify IIMs …

As with the treatment of many immune-mediated diseases, managing myositis encompasses
diverse factors, which present a challenge to the physician caring for these patients. The …

The adult and juvenile myositis syndromes, commonly referred to collectively as idiopathic
inflammatory myopathies (IIMs), are systemic autoimmune diseases with the hallmarks of …

Objectives To study the effects of abatacept on disease activity and on muscle biopsy
features of adult patients with dermatomyositis (DM) or polymyositis (PM). Methods Twenty …