Mercury (Hg) toxicity continues to represent a global health concern. Given that human
populations are mostly exposed to low chronic levels of mercurial compounds …

Abstract N-acetylcysteine (NAC), a cysteine pro-drug and glutathione precursor has been
used in therapeutic practices for several decades, as a mucolytic agent and for the treatment …

The initial steps in preclinical drug developing research concern the synthesis of new
compounds for specific therapeutic use which needs to be confirmed by in vitro and then in …

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
cardinal features of tremor, bradykinesia, rigidity, and postural instability, in addition to other …

Parkinson's disease (PD) is a multifactorial disorder with a complex etiology including
genetic risk factors, environmental exposures, and aging. While energy failure and oxidative …

Paraquat is a highly toxic herbicide that selectively accumulates in the lungs and causes
pulmonary damage through the oxidative and inflammatory processes. Carvedilol is a …

In this study, we demonstrated the protective effects of β-hydroxybutyrate (β-HB) against
paraquat (PQ)-induced kidney injury and elucidated the underlying molecular mechanisms …

In this study, we used purine hydrazone derivatives and coumarin aldehyde to synthesize a
novel fluorescent sensor (EDTP) by Schiff base reaction, which exhibited significant …

The objective of our study was to examine testicular toxicity of cadmium (Cd), focusing on
oxidative stress (OS), essential metals and androgenic status and morphological changes …

В монографии обобщены современные данные о метаболических механизмах
функционирования клеток иммунной системы при различных иммунопатологических …