[HTML][HTML] Kinetic models in industrial biotechnology–improving cell factory performance

J Almquist, M Cvijovic, V Hatzimanikatis, J Nielsen… - Metabolic …, 2014 - Elsevier
An increasing number of industrial bioprocesses capitalize on living cells by using them as
cell factories that convert sugars into chemicals. These processes range from the production …

Anaerobic fermentation of glycerol: a platform for renewable fuels and chemicals

JM Clomburg, R Gonzalez - Trends in biotechnology, 2013 - cell.com
To ensure the long-term viability of biorefineries, it is essential to go beyond the
carbohydrate-based platform and develop complementing technologies capable of …

Formulation, construction and analysis of kinetic models of metabolism: A review of modelling frameworks

PA Saa, LK Nielsen - Biotechnology advances, 2017 - Elsevier
Kinetic models are critical to predict the dynamic behaviour of metabolic networks.
Mechanistic kinetic models for large networks remain uncommon due to the difficulty of fitting …

Improving biohydrogen productivity by microbial dark-and photo-fermentations: novel data and future approaches

K Trchounian, RG Sawers, A Trchounian - Renewable and Sustainable …, 2017 - Elsevier
Hydrogen (H 2) is an effective, environmentally friendly and renewable source of fuel that
can be produced during dark-and photo-fermentation by different facultative and obligate …

Heterotrophic growth of Neochloris oleoabundans using glucose as a carbon source

D Morales-Sánchez, R Tinoco-Valencia, J Kyndt… - Biotechnology for …, 2013 - Springer
Background In comparison with phototrophic growth, heterotrophic conditions can
significantly increase growth rates, final cell number and cell mass in microalgae cultures …

Toward glycerol biorefinery: metabolic engineering for the production of biofuels and chemicals from glycerol

Z Chen, D Liu - Biotechnology for biofuels, 2016 - Springer
As an inevitable by-product of the biofuel industry, glycerol is becoming an attractive
feedstock for biorefinery due to its abundance, low price and high degree of reduction …

Flux analysis and metabolomics for systematic metabolic engineering of microorganisms

Y Toya, H Shimizu - Biotechnology advances, 2013 - Elsevier
Rational engineering of metabolism is important for bio-production using microorganisms.
Metabolic design based on in silico simulations and experimental validation of the metabolic …

Hydrogen production from glycerol by Escherichia coli and other bacteria: an overview and perspectives

K Trchounian, A Trchounian - Applied Energy, 2015 - Elsevier
Hydrogen (H 2) is a clean, effective and renewable fuel which can be produced by different
methods including biological ones, namely fermentation and biophotolysis. To improve …

Physiology and Bioenergetics of [NiFe]-Hydrogenase 2-Catalyzed H2-Consuming and H2-Producing Reactions in Escherichia coli

C Pinske, M Jaroschinsky, S Linek, CL Kelly… - Journal of …, 2015 - Am Soc Microbiol
Escherichia coli uptake hydrogenase 2 (Hyd-2) catalyzes the reversible oxidation of H2 to
protons and electrons. Hyd-2 synthesis is strongly upregulated during growth on glycerol or …

Mechanisms for hydrogen production by different bacteria during mixed-acid and photo-fermentation and perspectives of hydrogen production biotechnology

A Trchounian - Critical reviews in biotechnology, 2015 - Taylor & Francis
H2 has a great potential as an ecologically-clean, renewable and capable fuel. It can be
mainly produced via hydrogenases (Hyd) by different bacteria, especially Escherichia coli …