Multidisciplinary approaches in electronic nicotine delivery systems pulmonary toxicology: emergence of living and non-living bioinspired engineered systems

KH Benam - Communications Engineering, 2024 - nature.com
Technology-based platforms offer crucial support for regulatory agencies in overseeing
tobacco products to enhance public health protection. The use of electronic nicotine delivery …

Tobacco and menthol flavored nicotine-free electronic cigarettes induced inflammation and dysregulated repair in lung fibroblast and epithelium

Q Wang, JH Lucas, C Pang, R Zhao, I Rahman - Respiratory Research, 2024 - Springer
Background Electronic cigarette (e-cig) vaping has increased in the past decade in the US,
and e-cig use is misleadingly marketed as a safe cessation for quitting smoking. The main …

Precision cut lung slices: an integrated ex vivo model for studying lung physiology, pharmacology, disease pathogenesis and drug discovery

C Koziol-White, E Gebski, G Cao, RA Panettieri Jr - Respiratory Research, 2024 - Springer
Abstract Precision Cut Lung Slices (PCLS) have emerged as a sophisticated and
physiologically relevant ex vivo model for studying the intricacies of lung diseases, including …

Precision-Cut Lung Slices: Emerging Tools for Preclinical and Translational Lung Research: An Official American Thoracic Society Workshop Report

M Lehmann, R Krishnan, J Sucre… - American Journal of …, 2025 - atsjournals.org
The urgent need for effective treatments for acute and chronic lung diseases underscores
the significance of developing innovative preclinical human research tools. The 2023 …

Cooperation of immune regulators Tollip and surfactant protein A inhibits influenza a virus infection in mice

N Schaunaman, D Cervantes, T Nichols, M Numata… - Respiratory …, 2024 - Springer
Abstract Background Influenza A virus (IAV) infection is a significant risk factor for respiratory
diseases, but the host defense mechanisms against IAV remain to be defined. Immune …

Single cell RNA-sequencing of human precision-cut lung slices: A novel approach to study the effect of vaping and viral infection on lung health

T Crue, GY Lee, JY Peng, N Schaunaman… - Innate …, 2023 - journals.sagepub.com
Vaping is an increasing health threat in the US and worldwide. The damaging impact of
vaping on the human distal lung has been highlighted by the recent epidemic of electronic …

[HTML][HTML] Tobacco and Menthol flavored electronic cigarettes induced inflammation and dysregulated repair in lung fibroblast and epithelium

Q Wang, JH Lucas, C Pang, R Zhao, I Rahman - Research Square, 2023 - ncbi.nlm.nih.gov
Background Electronic cigarette (e-cig) vaping has increased in the past decade in the US,
and e-cig use is misleadingly marketed as a safe cessation for quitting smoking. The main …

Porcine lung tissue slices: a culture model for PRCV infection and innate immune response investigations

S Li, Y Lu, S Yang, C Wang, J Yang, X Huang, G Chen… - AMB Express, 2024 - Springer
Respiratory coronaviruses (RCoVs) significantly threaten human health, necessitating the
development of an ex vivo respiratory culture system for investigating RCoVs infection. Here …