Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are a
family of small conserved eukaryotic proteins that mediate membrane fusion between …

SNARE proteins and Sec1/Munc18 (SM) proteins constitute the core molecular engine that
drives nearly all intracellular membrane fusion and exocytosis. While SNAREs are known to …

Extensive research has yielded crucial insights into the mechanism of neurotransmitter
release, and working models for the functions of key proteins involved in release. The …

Research for three decades and major recent advances have provided crucial insights into
how neurotransmitters are released by Ca2+‐triggered synaptic vesicle exocytosis, leading …

Intracellular membrane fusion is mediated in most cases by membrane-bridging complexes
of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) …

Neurotransmitter release is governed by proteins that have homo-logs in most types of
intracellular membrane fusion, including the Sec1/Munc18 protein Munc18-1 and the …

SNAREs (soluble NSF-attachment protein receptors) are generally acknowledged as central
components of membrane fusion reactions, but their precise function has remained …

During neurotransmitter release, the neuronal SNARE proteins synaptobrevin/VAMP,
syntaxin, and SNAP-25 form a four-helix bundle, the SNARE complex, that pulls the synaptic …

The compartmentalization of eukaryotic cells is reliant on the fidelity of vesicle-mediated
intracellular transport. Vesicles deliver their cargo via membrane fusion, a process requiring …

The release of neurotransmitters by Ca2+-triggered synaptic vesicle exocytosis is an
exquisitely regulated process that is fundamental for interneuronal communication. This …