Candida parapsilosis: from genes to the bedside

R Tóth, J Nosek, HM Mora-Montes… - Clinical microbiology …, 2019 - Am Soc Microbiol
Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …

Antifungal therapy: new advances in the understanding and treatment of mycosis

L Scorzoni, ACA de Paula e Silva, CM Marcos… - Frontiers in …, 2017 - frontiersin.org
The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Graphene/CuO2 Nanoshuttles with Controllable Release of Oxygen Nanobubbles Promoting Interruption of Bacterial Respiration

M Jannesari, O Akhavan… - … applied materials & …, 2020 - ACS Publications
An oxygen nanoshuttle based on a reduced graphene oxide/copper peroxide (rGO/CuO2)
nanocomposite has been presented to deliver in situ oxygen nanobubbles (O2 NBs) for …

Candida Species Biofilms' Antifungal Resistance

S Silva, CF Rodrigues, D Araújo, ME Rodrigues… - Journal of Fungi, 2017 - mdpi.com
Candida infections (candidiasis) are the most prevalent opportunistic fungal infection on
humans and, as such, a major public health problem. In recent decades, candidiasis has …

Fungal biofilm resistance

G Ramage, R Rajendran, L Sherry… - International journal of …, 2012 - Wiley Online Library
Fungal biofilm infections have become increasingly recognised as a significant clinical
problem. One of the major reasons behind this is the impact that these have upon treatment …

Genetic control of Candida albicans biofilm development

JS Finkel, AP Mitchell - Nature Reviews Microbiology, 2011 - nature.com
Candida species cause frequent infections owing to their ability to form biofilms—surface-
associated microbial communities—primarily on implanted medical devices. Increasingly …

Fungal biofilms, drug resistance, and recurrent infection

JV Desai, AP Mitchell… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
A biofilm is a surface-associated microbial community. Diverse fungi are capable of biofilm
growth. The significance of this growth form for infection biology is that biofilm formation on …

Anaerobic bacteria grow within Candida albicans biofilms and induce biofilm formation in suspension cultures

EP Fox, ES Cowley, CJ Nobile, N Hartooni… - Current biology, 2014 - cell.com
The human microbiome contains diverse microorganisms, which share and compete for the
same environmental niches [1, 2]. A major microbial growth form in the human body is the …

Recent advances in understanding the human fungal pathogen hypoxia response in disease progression

C Puerner, S Vellanki, JL Strauch… - Annual Review of …, 2023 - annualreviews.org
Fungal-mediated disease progression and antifungal drug efficacy are significantly
impacted by the dynamic infection microenvironment. At the site of infection, oxygen often …

Fungal biofilm architecture produces hypoxic microenvironments that drive antifungal resistance

CH Kowalski, KA Morelli, D Schultz… - Proceedings of the …, 2020 - National Acad Sciences
Human fungal infections may fail to respond to contemporary antifungal therapies in vivo
despite in vitro fungal isolate drug susceptibility. Such a discrepancy between in vitro …