Steps towards standardized quantification of adult neurogenesis
X Zhao, H van Praag - Nature communications, 2020 - nature.com
New neurons are generated in adult mammals. Adult hippocampal neurogenesis is
considered to play an important role in cognition and mental health. The number and …
considered to play an important role in cognition and mental health. The number and …
Exercise Promotes Tissue Regeneration: Mechanisms Involved and Therapeutic Scope
Exercise has well-recognized beneficial effects on the whole body. Previous studies suggest
that exercise could promote tissue regeneration and repair in various organs. In this review …
that exercise could promote tissue regeneration and repair in various organs. In this review …
Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway
Fragile X messenger ribonucleoprotein 1 protein (FMRP) binds many mRNA targets in the
brain. The contribution of these targets to fragile X syndrome (FXS) and related autism …
brain. The contribution of these targets to fragile X syndrome (FXS) and related autism …
Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development
Fragile X messenger ribonucleoprotein 1 protein (FMRP) deficiency leads to fragile X
syndrome (FXS), an autism spectrum disorder. The role of FMRP in prenatal human brain …
syndrome (FXS), an autism spectrum disorder. The role of FMRP in prenatal human brain …
A critical period of neuronal activity results in aberrant neurogenesis rewiring hippocampal circuitry in a mouse model of epilepsy
ZR Lybrand, S Goswami, J Zhu, V Jarzabek… - Nature …, 2021 - nature.com
In the mammalian hippocampus, adult-born granule cells (abGCs) contribute to the function
of the dentate gyrus (DG). Disruption of the DG circuitry causes spontaneous recurrent …
of the dentate gyrus (DG). Disruption of the DG circuitry causes spontaneous recurrent …
[HTML][HTML] 3D bioprinting of human neural tissues with functional connectivity
Probing how human neural networks operate is hindered by the lack of reliable human
neural tissues amenable to the dynamic functional assessment of neural circuits. We …
neural tissues amenable to the dynamic functional assessment of neural circuits. We …
Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures
Human pluripotent stem cell (hPSC)-derived retinal organoids (ROs) can efficiently and
reproducibly generate retinal neurons that have potential for use in cell replacement …
reproducibly generate retinal neurons that have potential for use in cell replacement …
Pleiotrophin ameliorates age-induced adult hippocampal neurogenesis decline and cognitive dysfunction
H Li, L Xu, W Jiang, X Qiu, H Xu, F Zhu, Y Hu, S Liang… - Cell Reports, 2023 - cell.com
Cognitive impairment has been associated with an age-related decline in adult hippocampal
neurogenesis (AHN). The molecular basis of declining neurogenesis in the aging …
neurogenesis (AHN). The molecular basis of declining neurogenesis in the aging …
Transcriptional dynamics orchestrating the development and integration of neurons born in the adult hippocampus
NB Rasetto, D Giacomini, AA Berardino… - Science …, 2024 - science.org
The adult hippocampus generates new granule cells (aGCs) with functional capabilities that
convey unique forms of plasticity to the preexisting circuits. While early differentiation of adult …
convey unique forms of plasticity to the preexisting circuits. While early differentiation of adult …
Mechanisms underlying the effect of voluntary running on adult hippocampal neurogenesis
Adult hippocampal neurogenesis is important for preserving learning and memory‐related
cognitive functions. Physical exercise, especially voluntary running, is one of the strongest …
cognitive functions. Physical exercise, especially voluntary running, is one of the strongest …