Why is obesity such a problem in the 21st century? The intersection of palatable food, cues and reward pathways, stress, and cognition
Abstract Changes in food composition and availability have contributed to the dramatic
increase in obesity over the past 30–40 years in developed and, increasingly, in developing …
increase in obesity over the past 30–40 years in developed and, increasingly, in developing …
Food reinforcement, delay discounting and obesity
Choice is a central construct in behavioral economics, with choice research divided into
choice of concurrent alternative reinforcers, which is conceptualized as relative reinforcing …
choice of concurrent alternative reinforcers, which is conceptualized as relative reinforcing …
Cafeteria diet is a robust model of human metabolic syndrome with liver and adipose inflammation: comparison to high‐fat diet
BP Sampey, AM Vanhoose, HM Winfield… - …, 2011 - Wiley Online Library
Obesity has reached epidemic proportions worldwide and reports estimate that American
children consume up to 25% of calories from snacks. Several animal models of obesity exist …
children consume up to 25% of calories from snacks. Several animal models of obesity exist …
The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: a new role for mesolimbic GLP-1 receptors
SL Dickson, RH Shirazi, C Hansson… - Journal of …, 2012 - Soc Neuroscience
The glucagon-like peptide 1 (GLP-1) system is a recently established target for type 2
diabetes treatment. In addition to regulating glucose homeostasis, GLP-1 also reduces food …
diabetes treatment. In addition to regulating glucose homeostasis, GLP-1 also reduces food …
Ghrelin directly targets the ventral tegmental area to increase food motivation
KP Skibicka, C Hansson, M Alvarez-Crespo, PA Friberg… - Neuroscience, 2011 - Elsevier
Ghrelin, a circulating orexigenic stomach-derived hormone, has recently been implicated in
extra-homeostatic feeding, increasing food reward and food-motivated behavior. The …
extra-homeostatic feeding, increasing food reward and food-motivated behavior. The …
Role of ghrelin in food reward: impact of ghrelin on sucrose self‐administration and mesolimbic dopamine and acetylcholine receptor gene expression
KP Skibicka, C Hansson, E Egecioglu… - Addiction …, 2012 - Wiley Online Library
The decision to eat is strongly influenced by non‐homeostatic factors such as food
palatability. Indeed, the rewarding and motivational value of food can override homeostatic …
palatability. Indeed, the rewarding and motivational value of food can override homeostatic …
Hedonic and incentive signals for body weight control
E Egecioglu, KP Skibicka, C Hansson… - Reviews in Endocrine …, 2011 - Springer
Here we review the emerging neurobiological understanding of the role of the brain's reward
system in the regulation of body weight in health and in disease. Common obesity is …
system in the regulation of body weight in health and in disease. Common obesity is …
Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced …
J Alsiö, PK Olszewski, AH Norbäck, ZEA Gunnarsson… - Neuroscience, 2010 - Elsevier
The nucleus accumbens (NAcc) mediates feeding reward; its activity reflects tastants'
hedonic value. NAcc dopamine guides immediate responses to reward, however, its …
hedonic value. NAcc dopamine guides immediate responses to reward, however, its …
Activation of the GLP-1 receptors in the nucleus of the solitary tract reduces food reward behavior and targets the mesolimbic system
JE Richard, RH Anderberg, A Göteson, FM Gribble… - PloS one, 2015 - journals.plos.org
The gut/brain peptide, glucagon like peptide 1 (GLP-1), suppresses food intake by acting on
receptors located in key energy balance regulating CNS areas, the hypothalamus or the …
receptors located in key energy balance regulating CNS areas, the hypothalamus or the …
Food addiction, hormones and blood biomarkers in humans: a systematic literature review
Background Food addiction may play a role in rising obesity rates in connection with
obesogenic environments and processed food availability, however the concept of food …
obesogenic environments and processed food availability, however the concept of food …