Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced science

Y Xiang, Z Guo, P Zhu, J Chen, Y Huang - Cancer medicine, 2019 - Wiley Online Library
Traditional Chinese medicine (TCM) has been practiced for thousands of years and at the
present time is widely accepted as an alternative treatment for cancer. In this review, we …

The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

Mediterranean-type dietary pattern and physical activity: The winning combination to counteract the rising burden of non-communicable diseases (NCDS)

G Caprara - Nutrients, 2021 - mdpi.com
Non-communicable diseases (NCDs)(mainly cardiovascular diseases, cancers, chronic
respiratory diseases and type 2 diabetes) are the main causes of death worldwide. Their …

Natural bioactive compounds targeting epigenetic pathways in cancer: a review on alkaloids, terpenoids, quinones, and isothiocyanates

N El Omari, S Bakrim, M Bakha, JM Lorenzo… - Nutrients, 2021 - mdpi.com
Cancer is one of the most complex and systemic diseases affecting the health of mankind,
causing major deaths with a significant increase. This pathology is caused by several risk …

Gender differences in oxidative stress in relation to cancer susceptibility and survival

A Allegra, S Caserta, S Genovese, G Pioggia… - Antioxidants, 2023 - mdpi.com
Genetic, developmental, biochemical, and environmental variables interact intricately to
produce sex differences. The significance of sex differences in cancer susceptibility is being …

Regulation of the Notch signaling pathway by natural products for cancer therapy

J Cai, Y Qiao, L Chen, Y Lu, D Zheng - The Journal of nutritional …, 2024 - Elsevier
The Notch signaling pathway is an evolutionarily conserved pathway that modulates normal
biological processes involved in cellular differentiation, apoptosis, and stem cell self …

Epigenetic regulatory mechanisms induced by resveratrol

GFS Fernandes, GDB Silva, AR Pavan, DE Chiba… - Nutrients, 2017 - mdpi.com
Resveratrol (RVT) is one of the main natural compounds studied worldwide due to its
potential therapeutic use in the treatment of many diseases, including cancer, diabetes …

Dietary antioxidants remodel DNA methylation patterns in chronic disease

M Beetch, S Harandi‐Zadeh, K Shen… - British journal of …, 2020 - Wiley Online Library
Chronic diseases account for over 60% of all deaths worldwide according to the World
Health Organization reports. Majority of cases are triggered by environmental exposures that …

Notch signaling pathway: a comprehensive prognostic and gene expression profile analysis in breast cancer

H Yousefi, A Bahramy, N Zafari, MR Delavar, K Nguyen… - BMC cancer, 2022 - Springer
Breast cancer is a complex disease exhibiting a great degree of heterogeneity due to
different molecular subtypes. Notch signaling regulates the differentiation of breast epithelial …

Anticancer effects of nutraceuticals in the Mediterranean diet: an epigenetic diet model

R Divella, A Daniele, E Savino… - Cancer Genomics & …, 2020 - cgp.iiarjournals.org
Epidemiological and clinical studies support the association between nutrition and
development or progression of different malignancies such as colon, breast, and prostate …