Background Delirium is the most common neuropsychiatric syndrome encountered by
clinicians dealing with older adults and the medically ill and is best characterized by 5 core …

Background Delirium is a common mental disorder, which is distressing and has serious
adverse outcomes in hospitalised patients. Prevention of delirium is desirable from the …

Delirium is a debilitating form of brain dysfunction frequently encountered in the intensive
care unit (ICU). It is associated with increased morbidity and mortality, longer lengths of stay …

Objective: To revise the “Clinical Practice Guidelines for the Sustained Use of Sedatives and
Analgesics in the Critically Ill Adult” published in Critical Care Medicine in 2002. Methods …

Purpose Delirium is common in the critically ill, highly distressing to patients and families
and associated with increased morbidity and mortality. Results of studies on preventative …

Currently, in developed countries, nights are excessively illuminated (light at night), whereas
daytime is mainly spent indoors, and thus people are exposed to much lower light intensities …

Critically ill patients frequently experience poor sleep, characterized by frequent disruptions,
loss of circadian rhythms, and a paucity of time spent in restorative sleep stages. Factors that …

Objectives: To determine if a quality improvement intervention improves sleep and
delirium/cognition. Design: Observational, pre–post design. Setting: A tertiary academic …

Dexmedetomidine is a potent alpha-2-adrenergic agonist, more selective than clonidine,
with widespread actions on the mammalian brain that include sedation, anaesthetic-sparing …

Delirium is a clinical syndrome occurring in heterogeneous patient populations. It affects 45–
87% of critical care patients and is often associated with adverse outcomes including …