Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact

Y Gao, K Peng, S Mitragotri - Advanced Materials, 2021 - Wiley Online Library
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …

Hydrogels in a historical perspective: From simple networks to smart materials

SJ Buwalda, KWM Boere, PJ Dijkstra, J Feijen… - Journal of controlled …, 2014 - Elsevier
Over the past decades, significant progress has been made in the field of hydrogels as
functional biomaterials. Biomedical application of hydrogels was initially hindered by the …

Myocardial tissue engineering with cells derived from human-induced pluripotent stem cells and a native-like, high-resolution, 3-dimensionally printed scaffold

L Gao, ME Kupfer, JP Jung, L Yang, P Zhang… - Circulation …, 2017 - Am Heart Assoc
Rationale: Conventional 3-dimensional (3D) printing techniques cannot produce structures
of the size at which individual cells interact. Objective: Here, we used multiphoton-excited …

Chemical cross-linking methods for cell encapsulation in hydrogels

C Echalier, L Valot, J Martinez, A Mehdi… - Materials Today …, 2019 - Elsevier
Cell-encapsulating hydrogels are of tremendous interest in regenerative medicine. Tissue
engineering relies on biomaterials able to act as artificial extracellular matrices to guide cells …

Spatiotemporally controllable and cytocompatible approach builds 3D cell culture matrix by photo‐uncaged‐thiol Michael addition reaction

Z Liu, Q Lin, Y Sun, T Liu, C Bao, F Li, L Zhu - Advanced Materials, 2014 - infona.pl
A new concept of photocrosslinking mechanism is developed to construct a 3D cell culture
matrix based on a photo‐uncaged‐thiol Michael addition. This first‐class approach not only …

Thiol-methylsulfone-based hydrogels for 3D cell encapsulation

JI Paez, A Farrukh, R Valbuena-Mendoza… - … applied materials & …, 2020 - ACS Publications
Thiol-maleimide and thiol-vinylsulfone cross-linked hydrogels are widely used systems in
3D culture models, in spite of presenting uncomfortable reaction kinetics for cell …

Thiol-Mediated Chemoselective Strategies for In Situ Formation of Hydrogels

J Su - Gels, 2018 - mdpi.com
Hydrogels are three-dimensional networks composed of hydrated polymer chains and have
been a material of choice for many biomedical applications such as drug delivery …

Whole organ engineering: approaches, challenges, and future directions

S Sohn, MV Buskirk, MJ Buckenmeyer, R Londono… - Applied Sciences, 2020 - mdpi.com
Featured Application The specific application of this review article is for the advancement of
commercially translatable technologies in the field of whole organ engineering. Abstract End …

3D printed pericardium hydrogels to promote wound healing in vascular applications

LG Bracaglia, M Messina, S Winston, CY Kuo… - …, 2017 - ACS Publications
Vascular grafts that can support total replacement and maintenance by the body of the
injured vessel would improve outcomes of major surgical reconstructions. Building scaffolds …

Thermoresponsive injectable hydrogels cross-linked by native chemical ligation

KWM Boere, BG Soliman, DTS Rijkers… - …, 2014 - ACS Publications
Temperature-induced physical gelation was combined with native chemical ligation (NCL)
as a chemical cross-linking mechanism to yield rapid network formation and mechanically …