Formation of benign tumors by stem cell deregulation
M Valet, P Narbonne - PLoS Genetics, 2022 - journals.plos.org
Within living organisms, stem cells respond to various cues, including to niche signals and
growth factors. Niche signals originate from the stem cell's microenvironment and promote …
growth factors. Niche signals originate from the stem cell's microenvironment and promote …
[HTML][HTML] Warning signs from the crypt: aberrant protein glycosylation marks opportunities for early colorectal cancer detection
D Chandrasekar, C Guerrier… - Clinical and …, 2023 - journals.lww.com
Colorectal cancer (CRC) remains a leading cause of cancer-related deaths despite being
the most preventable and treatable forms of cancer when caught early through screening …
the most preventable and treatable forms of cancer when caught early through screening …
[HTML][HTML] ALG2 inhibits the epithelial-to-mesenchymal transition and stemness of ovarian granulosa cells through the Wnt/β-catenin signaling pathway in polycystic …
Q Zheng, M Liu, J Fu - Reproductive Biology, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects fertility in women of
reproductive age, and a leading cause of anovulatory infertility. Ovarian granulosa cells are …
reproductive age, and a leading cause of anovulatory infertility. Ovarian granulosa cells are …
B3GNT7 regulates mucin O-glycosylation to alleviate colonic inflammation
T Wang, H Sun, M Zhang, P Shen, Y Li - BMC gastroenterology, 2024 - Springer
Background B3GNT7, a glycosyltransferase of significant importance that is highly
expressed in intestinal epithelial cells, plays a pivotal role in intestinal physiological …
expressed in intestinal epithelial cells, plays a pivotal role in intestinal physiological …
[HTML][HTML] Inflammation-Induced Cellular Changes: Genetic Mutations, Oncogene Impact, and Novel Glycoprotein Biomarkers
X Wang, Y Shen, Y Chen, S Yang - Advances in Biomarker Sciences and …, 2024 - Elsevier
Persistent inflammation can trigger the development of colorectal cancer, especially in
patients with inflammatory bowel disease (IBD). The precise molecular mechanisms …
patients with inflammatory bowel disease (IBD). The precise molecular mechanisms …
Tumor-and immune-derived N-acetyl-β-D-hexosaminidase drive colorectal cancer and stratify patient risk
Non-invasive prognostic markers are needed to improve survival of colorectal cancer (CRC)
patients. Towards this goal, we applied integrative systems glycobiology approaches to …
patients. Towards this goal, we applied integrative systems glycobiology approaches to …
Formation of benign tumours by stem cell misregulation
M Valet, P Narbonne - 2022 - preprints.org
Our tissues usually have just the right number of cells to optimally fulfil their function. Not
enough cells within a tissue can lead to dysfunction, while too many cells result in a tumour …
enough cells within a tissue can lead to dysfunction, while too many cells result in a tumour …