Regulation of cardiac Cav1. 2 channels by calmodulin
M Kameyama, E Minobe, D Shao, J Xu, Q Gao… - International Journal of …, 2023 - mdpi.com
Cav1. 2 Ca2+ channels, a type of voltage-gated L-type Ca2+ channel, are ubiquitously
expressed, and the predominant Ca2+ channel type, in working cardiac myocytes. Cav1. 2 …
expressed, and the predominant Ca2+ channel type, in working cardiac myocytes. Cav1. 2 …
Regulation of ErbB Receptors by the Ca2+ Sensor Protein Calmodulin in Cancer
A Villalobo - Biomedicines, 2023 - mdpi.com
Overexpression and mutations of the epidermal growth factor receptor (EGFR/ErbB1/HER1)
and other tyrosine kinase receptors of the ErbB family (ErbB2/HER2, ErbB3/HER3 and …
and other tyrosine kinase receptors of the ErbB family (ErbB2/HER2, ErbB3/HER3 and …
Acute phosphatidylinositol 4,5 bisphosphate depletion destabilizes sarcolemmal expression of cardiac L-type Ca2+ channel CaV1.2
TL Voelker, SG Del Villar, M Westhoff… - Proceedings of the …, 2023 - National Acad Sciences
CaV1. 2 channels are critical players in cardiac excitation–contraction coupling, yet we do
not understand how they are affected by an important therapeutic target of heart failure …
not understand how they are affected by an important therapeutic target of heart failure …
Retinal cyclic nucleotide-gated channel regulation by calmodulin
A Bej, JB Ames - International Journal of Molecular Sciences, 2022 - mdpi.com
Retinal cyclic nucleotide-gated (CNG) ion channels bind to intracellular cGMP and mediate
visual phototransduction in photoreceptor rod and cone cells. Retinal rod CNG channels …
visual phototransduction in photoreceptor rod and cone cells. Retinal rod CNG channels …
Arrhythmogenic calmodulin variants D131E and Q135P disrupt interaction with the L‐type voltage‐gated Ca2+ channel (Cav1.2) and reduce Ca2+‐dependent …
N Gupta, EMB Richards, VS Morris, R Morris… - Acta …, 2025 - Wiley Online Library
Abstract Aim Long QT syndrome (LQTS) and catecholaminergic polymorphism ventricular
tachycardia (CPVT) are inherited cardiac disorders often caused by mutations in ion …
tachycardia (CPVT) are inherited cardiac disorders often caused by mutations in ion …
CaM‐dependent modulation of human CaV1.3 whole‐cell and single‐channel currents by C‐terminal CaMKII phosphorylation site S1475
S Salamon, E Kuzmenkina, C Fried… - The Journal of …, 2024 - Wiley Online Library
Phosphorylation enables rapid modulation of voltage‐gated calcium channels (VGCC) in
physiological and pathophysiological conditions. How phosphorylation modulates human …
physiological and pathophysiological conditions. How phosphorylation modulates human …
Calmodulin promotes a Ca2+‐dependent conformational change in the C‐terminal regulatory domain of CaV1.2
DK Yadav, DE Anderson, JW Hell, JB Ames - FEBS letters, 2022 - Wiley Online Library
Calmodulin (CaM) binds to the membrane‐proximal cytosolic C‐terminal domain of CaV1. 2
(residues 1520–1669, CT (1520–1669)) and causes Ca2+‐induced conformational changes …
(residues 1520–1669, CT (1520–1669)) and causes Ca2+‐induced conformational changes …
Structural Insights into the Regulation of the L-type Voltage-gated Channel CaV1. 2 by Half-Calcified Calmodulin (CaM) and Calcium-binding Protein 1 (CaBP1)
I Salveson - 2023 - escholarship.org
The L-type voltage gated calcium channel CaV1. 2 is expressed in smooth and cardiac
muscle, as well as in neurons where it regulates neuronal excitability and synaptic …
muscle, as well as in neurons where it regulates neuronal excitability and synaptic …