Optimal perioperative pain control for total joint arthroplasty remains a challenge. Whereas
traditional regimens have relied heavily on opioids, newer multimodal pathways are …

Background Oral multimodal analgesia for hip and knee arthroplasty is increasingly used as
part of enhanced recovery protocols designed to minimize early postoperative pain and to …

With increasing awareness of both short-and long-term problems associated with liberal
perioperative opioid administration, the need for routinely and clinically feasible alternatives …

Cardiac surgery is associated with significant postoperative pain, which complicates
recovery. The unique aspects of cardiac surgical pain include multiple sites of pain, initial …

Methods: Literature searches were performed using PubMed, EBSCO, Cochrane Review,
and Google Scholar without publication date limits. Of 264,617 articles' titles screened and …

In the multimodal approach to the management of postoperative pain, local infiltration and
regional blocks have been increasingly utilized for pain control. One of the limitations of …

Over the past 2 decades, many new techniques and drugs for the treatment of acute pain
have achieved widespread use. The main aim of this study was to assess the progress in …

Respiratory depression is common in patients recovering from surgery and anaesthesia.
Failure to recognise and lack of timely institution of intervention can lead to catastrophic …

Background Risk of stroke-related morbidity and mortality increases significantly with age.
Aging is associated with chronic, low-grade inflammation, which is thought to contribute to …

BACKGROUND Multimodal analgesia regimens have been suggested to improve pain
control and reduce opioid consumption after surgery. OBJECTIVE To institutionally …