Age-appropriate functions and dysfunctions of the neonatal neutrophil

SM Lawrence, R Corriden, V Nizet - Frontiers in pediatrics, 2017 - frontiersin.org
Neonatal and adult neutrophils are distinctly different from one another due to well-defined
and documented deficiencies in neonatal cells, including impaired functions, reduced …

How I manage children with neutropenia

DC Dale - British journal of haematology, 2017 - Wiley Online Library
Neutropenia, usually defined as a blood neutrophil count< 1· 5× 109/l, is a common medical
problem for children and adults. There are many causes for neutropenia, and at each stage …

An IL-10/DEL-1 axis supports granulopoiesis and survival from sepsis in early life

E Vergadi, O Kolliniati, I Lapi, E Ieronymaki… - Nature …, 2024 - nature.com
The limited reserves of neutrophils are implicated in the susceptibility to infection in
neonates, however the regulation of neutrophil kinetics in infections in early life remains …

Human milk growth factors and their role in NEC prevention: a narrative review

DJ York, AL Smazal, DT Robinson, IG De Plaen - Nutrients, 2021 - mdpi.com
Growing evidence demonstrates human milk's protective effect against necrotizing
enterocolitis (NEC). Human milk derives these properties from biologically active …

Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials

CJ Henry, G Semova, E Barnes, I Cotter, T Devers… - Pediatric …, 2022 - nature.com
Background The lack of a consensus definition of neonatal sepsis and a core outcome set
(COS) proves a substantial impediment to research that influences policy and practice …

Neonatal alloimmune neutropenia

L Porcelijn, M de Haas - Transfusion Medicine and Hemotherapy, 2018 - karger.com
Neonatal alloimmune neutropenia (NAIN, NAIN or NIN) is a neutrophil blood group
antagonism, analogous to hemolytic disease of the fetus and newborn (HDFN) and …

Granulocyte-colony stimulating factor GCSF mobilizes hematopoietic stem cells in Kasai patients with biliary atresia in a phase 1 study and improves short term …

AX Holterman, HPA Nguyen, E Nadler, GH Vu… - Journal of Pediatric …, 2021 - Elsevier
Aims In RCT of adults with decompensated cirrhosis, GCSF mobilizes hematopoietic stem
cells HSC and improves short-term outcome. An FDA-IND for sequential Kasai-GCSF …

[HTML][HTML] Insight Into Neonatal Sepsis: An Overview

HAH Mahmoud, R Parekh, S Dhandibhotla, T Sai… - Cureus, 2023 - ncbi.nlm.nih.gov
There are approximately 1.3 million cases of neonatal sepsis reported worldwide with
deaths occurring more commonly in preterm and low-weight newborns. Neonatal sepsis is …

Adjunctive therapy to treat neonatal sepsis

S Esposito, N Principi - Expert review of clinical pharmacology, 2020 - Taylor & Francis
Introduction: Neonatal sepsis (NS) is a very severe condition that causes significant
morbidity and mortality. Areas covered: To overcome the limits of antibiotic therapy and …

Neonatal immune incompatibilities between newborn and mother

B Arneth - Journal of clinical medicine, 2020 - mdpi.com
Background: Incompatibilities between the mother and unborn baby can cause
complications that must be identified early to initiate the appropriate treatment. For example …