Natural killer cells, viruses and cancer
A Cerwenka, LL Lanier - Nature reviews immunology, 2001 - nature.com
Natural killer cells are innate immune cells that control certain microbial infections and
tumours. The function of natural killer cells is regulated by a balance between signals …
tumours. The function of natural killer cells is regulated by a balance between signals …
SLAM family receptors and SAP adaptors in immunity
JL Cannons, SG Tangye… - Annual review of …, 2011 - annualreviews.org
The signaling lymphocyte activation molecule (SLAM)-associated protein, SAP, was first
identified as the protein affected in most cases of X-linked lymphoproliferative (XLP) …
identified as the protein affected in most cases of X-linked lymphoproliferative (XLP) …
SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor …
JM Chemnitz, RV Parry, KE Nichols… - The Journal of …, 2004 - journals.aai.org
To study the cis-and trans-acting factors that mediate programmed death 1 (PD-1) signaling
in primary human CD4 T cells, we constructed a chimeric molecule consisting of the murine …
in primary human CD4 T cells, we constructed a chimeric molecule consisting of the murine …
T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells
T Chtanova, SG Tangye, R Newton, N Frank… - The Journal of …, 2004 - journals.aai.org
Effector T cell responses have long been viewed in the context of the Th1/Th2 paradigm.
Recently, a third major subset of nonpolarized effector T cells that provides help to B cells …
Recently, a third major subset of nonpolarized effector T cells that provides help to B cells …
SLAM-family receptors come of age as a potential molecular target in cancer immunotherapy
P Farhangnia, SM Ghomi, S Mollazadehghomi… - Frontiers in …, 2023 - frontiersin.org
The signaling lymphocytic activation molecule (SLAM) family receptors were discovered in
immune cells for the first time. The SLAM-family receptors are a significant player in …
immune cells for the first time. The SLAM-family receptors are a significant player in …
The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease
SAP (signalling lymphocytic activation molecule (SLAM)-associated protein) is a T-and
natural killer (NK)-cell-specific protein containing a single SH2 domain encoded by a gene …
natural killer (NK)-cell-specific protein containing a single SH2 domain encoded by a gene …
SAP couples Fyn to SLAM immune receptors
SAP (SLAM-associated protein) is a small lymphocyte-specific signalling molecule that is
defective or absent in patients with X-linked lymphoproliferative syndrome (XLP) …
defective or absent in patients with X-linked lymphoproliferative syndrome (XLP) …
The dual-function CD150 receptor subfamily: the viral attraction
SP Sidorenko, EA Clark - Nature immunology, 2003 - nature.com
The CD150 subfamily within the CD2 family is a growing group of dual-function receptors
that have within their cytoplasmic tails a characteristic signaling motif. The ITSM …
that have within their cytoplasmic tails a characteristic signaling motif. The ITSM …
Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules
SAP (SLAM-associated protein) was identified in 1998 as an adaptor molecule involved in
the intracellular signaling pathways elicited through the cell surface receptor SLAM and as …
the intracellular signaling pathways elicited through the cell surface receptor SLAM and as …
Immune regulation by SLAM family receptors and SAP-related adaptors
A Veillette - Nature Reviews Immunology, 2006 - nature.com
The signalling lymphocytic activation molecule (SLAM) family of receptors is expressed by a
wide range of immune cells. Through their cytoplasmic domain, SLAM family receptors …
wide range of immune cells. Through their cytoplasmic domain, SLAM family receptors …