Background Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder of
unknown etiology; although infection and inflammation have recently been considered as …

Irritable bowel syndrome (IBS) is characterized as functional because a pathobiological
cause is not readily apparent. Considerable evidence, however, documents that sensitizing …

OBJECTIVES: Evidence suggests that patients with irritable bowel syndrome (IBS) have an
altered cytokine profile, although it is unclear whether cytokines are linked with symptom …

Intestinal epithelial barrier function is closely associated with the development of many
intestinal diseases. Heat-killed Lacticaseibacillus paracasei (HK-LP) has been shown to …

Background and objectives: immune system alteration in irritable bowel syndrome (IBS)
patients may be modulated by probiotics. We assessed the efficacy of some probiotic …

Methods Expression of TLRs and cytokines was assessed in 47 IBS patients (Rome III) and
25 controls using quantitative real-time polymerase chain reaction. Immunohistochemistry …

Cross-cultural factors are important in functional gastrointestinal disorders (FGIDs). In the
setting of FGIDs, the aims of this review were as follows:(1) to engender interest in global …

Objective In women presenting to gynaecological clinics with lower abdominal pain, the
cause is frequently attributed to endometriosis irrespective of whether it is found to be …

Visceral allodynia and increased colonic permeability are considered to be crucial
pathophysiology of irritable bowel syndrome (IBS). Corticotropin-releasing factor (CRF) and …

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a multifactorial chronic
gastrointestinal disorder characterized by inflammation and immune response. In this …