Deciphering cell-type heterogeneity is crucial for systematically understanding tissue
homeostasis and its dysregulation in diseases. Computational deconvolution is an efficient …

The intersection between the human oral microbiome and oral health is an emerging area of
study which has gained momentum over the last decade. This momentum has motivated a …

Background Changes in cell-type composition of tissues are associated with a wide range of
diseases and environmental risk factors and may be causally implicated in disease …

Importance Children with developmental delays are at a heightened risk of experiencing
mental health challenges, and this risk is exacerbated among racially minoritized children …

Objective To examine longitudinal associations between early life threat and deprivation on
epigenetic age acceleration at ages 9 and 15 years, and to examine associations of age …

Self-control is a personality dimension that is associated with better physical health and a
longer lifespan. Here, we examined (1) whether self-control is associated with buccal and …

Early-life adversity increases the risk of health problems. Interventions supporting protective
and responsive caregiving offer a promising approach to attenuating adversity-induced …

Recently, biological aging has been quantified in DNA-methylation samples of older adults
and applied as so-called “methylation profile scores”(MPSs) in separate target samples …

Background Early detection of esophageal cancer is critical to improve survival. Whilst
studies have identified biomarkers, their interpretation and validity is often confounded by …

Cheek swabs, heterogeneous samples consisting primarily of buccal epithelial cells, are
widely used in pediatric DNA methylation studies and biomarker creation. However, the …