Investigation on the interaction of aromatic organophosphate flame retardants with human serum albumin via computer simulations, multispectroscopic techniques …

X Ma, L Kuang, X Wang, Z Zhang, C Chen… - International Journal of …, 2023 - Elsevier
Organophosphate flame retardants (OPFRs) are newly emerging estrogenic environmental
pollutants, which attracted widespread public interest owing to their potential threats to …

Molecular insight on the binding of halogenated organic phosphate esters to human serum albumin and its effect on cytotoxicity of halogenated organic phosphate …

Z Zhang, L Dai, K Yang, J Luo, Y Zhang, P Ding… - International Journal of …, 2024 - Elsevier
Abstract Halogenated Organic Phosphate Esters (OPEs) are commonly found in plasticizers
and flame retardants. However, they are one kind of persistent contaminants that can pose a …

Impacts of Halogen Substitutions on Bisphenol A Compounds Interaction with Human Serum Albumin: Exploring from Spectroscopic Techniques and Computer …

H Zhang, R Cai, C Chen, L Gao, P Ding, L Dai… - International Journal of …, 2023 - mdpi.com
Bisphenol A (BPA) is an endocrine-disrupting compound, and the binding mechanism of
BPA with carrier proteins has drawn widespread attention. Halogen substitutions can …

Evidence of enhanced inhibitory potential of Ferulic Acid Ethyl Ester towards modulating fibrillation and disassembling insulin fibrils

S Malik, F Nabi, MK Siddiqi, A Masroor… - Journal of Molecular …, 2023 - Elsevier
The conversion of native conformation of protein into proteotoxic insoluble entities is not only
confined to the protein misfolding diseases (PMDs) but also associated with …

Revelation of anti-aggregating and disaggregating characteristic of amodiaquine via inhibition of human lysozyme fibrillation: Therapeutic alternative for treating …

N Majid, MK Siddiqi, S Malik, RH Khan - Journal of Molecular Liquids, 2023 - Elsevier
Amyloidopathies are associated with a biochemical change in concerned organ or bio-
environment known as inflammation (promoted in case of fibrils accumulation due to their …

Inhibition of primary and secondary nucleation alongwith disruption of amyloid fibrils and alleviation of associated cytotoxicity: A biophysical insight of a novel property …

N Majid, MK Siddiqi, MN Hassan, S Malik, S Khan… - Biomaterials …, 2023 - Elsevier
Aggregation of physiologically synthesized soluble proteins to insoluble, cytotoxic fibrils is a
pre-requisite for pathogenesis of amyloid associated disorders including Alzheimer's …