Separable nonlinear least squares: the variable projection method and its applications

G Golub, V Pereyra - Inverse problems, 2003 - iopscience.iop.org
In this paper we review 30 years of developments and applications of the variable projection
method for solving separable nonlinear least-squares problems. These are problems for …

Issues of spectral quality in clinical 1H‐magnetic resonance spectroscopy and a gallery of artifacts

R Kreis - NMR in Biomedicine, 2004 - Wiley Online Library
In spite of the facts that magnetic resonance spectroscopy (MRS) is applied as clinical tool in
non‐specialized institutions and that semi‐automatic acquisition and processing tools can …

Modulation of GABA and resting state functional connectivity by transcranial direct current stimulation

V Bachtiar, J Near, H Johansen-Berg, CJ Stagg - elife, 2015 - elifesciences.org
We previously demonstrated that network level functional connectivity in the human brain
could be related to levels of inhibition in a major network node at baseline. In this study, we …

Real-time metabolic imaging

K Golman, R in 't Zandt… - Proceedings of the …, 2006 - National Acad Sciences
The endogenous substance pyruvate is of major importance to maintain energy
homeostasis in the cells and provides a window to several important metabolic processes …

Metabolic Imaging by Hyperpolarized 13C Magnetic Resonance Imaging for In vivo Tumor Diagnosis

K Golman, R Zandt, M Lerche, R Pehrson… - Cancer research, 2006 - AACR
The “Warburg effect,” an elevation in aerobic glycolysis, may be a fundamental property of
cancer cells. For cancer diagnosis and treatment, it would be valuable if elevated glycolytic …

Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: background and experts' consensus recommendations

R Kreis, V Boer, IY Choi, C Cudalbu… - NMR in …, 2021 - Wiley Online Library
With a 40‐year history of use for in vivo studies, the terminology used to describe the
methodology and results of magnetic resonance spectroscopy (MRS) has grown …

1H MR Spectroscopy of the Brain: Absolute Quantification of Metabolites1

JFA Jansen, WH Backes, K Nicolay, ME Kooi - Radiology, 2006 - pubs.rsna.org
Hydrogen 1 (1H) magnetic resonance (MR) spectroscopy enables noninvasive in vivo
quantification of metabolite concentrations in the brain. Currently, metabolite concentrations …

Time‐domain semi‐parametric estimation based on a metabolite basis set

H Ratiney, M Sdika, Y Coenradie… - NMR in Biomedicine …, 2005 - Wiley Online Library
A novel and fast time‐domain quantitation algorithm—quantitation based on semi‐
parametric quantum estimation (QUEST)—invoking optimal prior knowledge is proposed …

A review of machine learning applications for the proton MR spectroscopy workflow

DMJ van de Sande, JP Merkofer… - Magnetic …, 2023 - Wiley Online Library
This literature review presents a comprehensive overview of machine learning (ML)
applications in proton MR spectroscopy (MRS). As the use of ML techniques in MRS …

In vivo quantification of choline compounds in the breast with 1H MR spectroscopy

PJ Bolan, S Meisamy, EH Baker, J Lin… - … in Medicine: An …, 2003 - Wiley Online Library
This work describes a methodology for quantifying levels of total choline‐containing
compounds (tCho) in the breast using in vivo 1H MR spectroscopy (MRS) at high field (4 …