Metallodrugs offer potential for unique mechanism of drug action based on the choice of the
metal, its oxidation state, the types and number of coordinated ligands and the coordination …

The discovery of cisplatin (cis-Pt (NH 3) 2 Cl 2) as an antineoplastic agent has focussed
attention on the rational design of metal complexes that can be potentially used in cancer …

Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

Highlights•TNBC is an unmet medical need with poor survival rates and no targeted
therapy.•TNBC resists conventional chemotherapy and surgical strategies.•A review of 121 …

The main purpose of this article is to focus on the diversity created by substitution on
pyridine rings of 2, 2′: 6′, 2 ″-terpyridines (tpy) allowing a fine-tuning of the ligand …

This article provides a comprehensive review of palladium compounds that have been
evaluated for anticancer activity in vivo or in vitro from the era of discovery of cisplatin up to …

This review focuses on studies of coordination and organometallic compounds as potential
chemotherapeutics against triple negative breast cancer (TNBC) which has one of the …

Terpyridine complexes are known for their broad biological activities, of which their
anticancer potency is the most extensively studied. Strikingly, free ligand activity has rarely …

Based on the chemotherapeutic success of cisplatin, carboplatin and oxaliplatin as
anticancer drugs, and silver sulfadiazine (AgSDZ) as an antibacterial drug, exploration of the …

The use of cisplatin and its derivatives in cancer treatment triggered the interest in metal-
containing complexes as potential novel anticancer agents. Palladium (II)-based complexes …