Photoacoustically guided wavefront shaping for enhanced optical focusing in scattering media

P Lai, L Wang, JW Tay, LV Wang - Nature photonics, 2015 - nature.com
Non-invasively focusing light into strongly scattering media, such as biological tissue, is
highly desirable but challenging. Recently, ultrasonically guided wavefront-shaping …

Focusing through dynamic tissue with millisecond digital optical phase conjugation

D Wang, EH Zhou, J Brake, H Ruan, M Jang, C Yang - Optica, 2015 - opg.optica.org
Digital optical phase conjugation (DOPC) is a new technique employed in wavefront
shaping and phase conjugation for focusing light through or within scattering media such as …

[HTML][HTML] Optical focusing deep inside dynamic scattering media with near-infrared time-reversed ultrasonically encoded (TRUE) light

Y Liu, P Lai, C Ma, X Xu, AA Grabar, LV Wang - Nature communications, 2015 - nature.com
Focusing light deep inside living tissue has not been achieved despite its promise to play a
central role in biomedical imaging, optical manipulation and therapy. To address this …

Breaking acoustic limit of optical focusing using photoacoustic‐guided wavefront shaping

R Gao, Z Xu, L Song, C Liu - Laser & Photonics Reviews, 2021 - Wiley Online Library
Optical wavefront shaping (WFS) has been demonstrated as a powerful tool for focusing
light in opaque scattering media. Photoacoustic (PA)‐guided WFS, in particular, has raised a …

[HTML][HTML] All-optical phase conjugation using diffractive wavefront processing

CY Shen, J Li, T Gan, Y Li, M Jarrahi… - Nature Communications, 2024 - nature.com
Optical phase conjugation (OPC) is a nonlinear technique used for counteracting wavefront
distortions, with applications ranging from imaging to beam focusing. Here, we present a …

[HTML][HTML] Perspective: Wavefront shaping techniques for controlling multiple light scattering in biological tissues: Toward in vivo applications

JH Park, Z Yu, KR Lee, P Lai, YK Park - APL photonics, 2018 - pubs.aip.org
Light scattering is a fundamental physical phenomenon and also plays critical roles in
optical imaging. To optically visualize an object, waves scattered from individual positions in …

Effects of light scattering on optical-resolution photoacoustic microscopy

Y Liu, C Zhang, LV Wang - Journal of Biomedical Optics, 2012 - spiedigitallibrary.org
The imaging depth of ballistic optical imaging technologies is limited by light scattering. To
study the effects of scattering on optical-resolution photoacoustic microscopy (OR-PAM), the …

[HTML][HTML] Time-reversed magnetically controlled perturbation (TRMCP) optical focusing inside scattering media

Z Yu, J Huangfu, F Zhao, M Xia, X Wu, X Niu, D Li… - Scientific reports, 2018 - nature.com
Manipulating and focusing light deep inside biological tissue and tissue-like complex media
has been desired for long yet considered challenging. One feasible strategy is through …

[HTML][HTML] Photoacoustic wavefront shaping with high signal to noise ratio for light focusing through scattering media

J Sun, B Zhang, Q Feng, H He, Y Ding, Q Liu - Scientific reports, 2019 - nature.com
Noninvasive light focusing and imaging through a scattering medium can be achieved by
wavefront shaping using the photoacoustic signal as feedback. Unfortunately, the signal to …

Focused fluorescence excitation with time-reversed ultrasonically encoded light and imaging in thick scattering media

P Lai, Y Suzuki, X Xu, LV Wang - Laser physics letters, 2013 - iopscience.iop.org
Scattering dominates light propagation in biological tissue, and therefore restricts both
resolution and penetration depth in optical imaging within thick tissue. As photons travel into …