Importance After initial resuscitation, critically ill children may accumulate fluid and develop
fluid overload. Accruing evidence suggests that fluid overload contributes to greater …

Abstract These European Resuscitation Council Paediatric Life Support (PLS) guidelines,
are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science …

Zusammenfassung Die Leitlinien des European Resuscitation Council (ERC) zu den
lebensrettenden Maßnahmen bei Kindern (Paediatric Life Support, PLS) basieren auf dem …

Objectives: To describe the characteristics of fluid accumulation in critically ill children and
evaluate the association between the degree, timing, duration, and rate of fluid accumulation …

Importance Identifying conditions that could be prioritized for research based on health care
system burden is important for developing a research agenda for the care of hospitalized …

Importance The research agenda in pediatric hospital medicine has seldom considered the
perspectives of young people, parents and caregivers, and health care professionals. Their …

Background Resuscitation with crystalloid fluid is a cornerstone of pediatric septic shock
treatment. However, the optimal type of crystalloid fluid is unknown. We aimed to determine …

Objective The objective of the study was to describe the origins, growth, and progress of a
national research network in pediatric emergency medicine. Methods The success of …

Background The impact of disorders of fluid balance, including the pathologic state of fluid
overload in sick children has become increasingly apparent. With this understanding, there …

Importance The COVID-19 pandemic created unprecedented challenges for clinical trials
worldwide, threatening premature closure and trial integrity. Every phase of research …