Purpose Although doxorubicin chemotherapy is commonly applied for treating different
malignant tumors, cardiotoxicity induced by this chemotherapeutic agent restricts its clinical …

BACKGROUND Given the disadvantages and limitations of current endometriosis therapy,
there is a progressive increase in studies focusing on plant-derived agents as a natural …

Silybum marianum (SM), a well-known plant used as both a medicine and a food, has been
widely used to treat various diseases, especially hepatic diseases. The seeds and fruits of …

Background Silymarin, a blend of flavonolignans isolated from plant Silybum marianum L.,
has long been used as an herbal medicine. Biogenic routes especially the plant-based …

Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …

Hepatocellular carcinoma (HCC) has been identified as one of the most deadly
malignancies with limited therapeutic efficacy worldwide. However, understanding the …

Ethnopharmacological relevance Interstitial lung disease (ILD) is a chronic lung dysfunction
disease with a poor prognosis and poor recovery. The clinically used therapeutic drugs …

Silymarin, a milk thistle extract, has anti-inflammatory, immunomodulatory, anti-lipid
peroxidative, anti-fibrotic, anti-oxidative, and anti-proliferative properties. Silymarin exhibits …

Introduction The development and application of novel therapeutic medicines for the
treatment of cancer are of vital importance to improve the disease< apos;> s outcome and …

The present work was designed to assess the efficacy of Silybum marianum total extract
(STE), silymarin (Sm), and silibinin (Sb) against experimentally induced renal …