It is well established that human pluripotent stem cells (hPSCs) can acquire genetic and
epigenetic changes during culture in vitro. Given the increasing use of hPSCs in research …

There is a rise in the number of people who have vision loss due to retinal diseases, and
conventional therapies for treating retinal degeneration fail to repair and regenerate the …

Introduction Spinal cord injury (SCI) can lead to severe neurological dysfunction. Despite
scientific and medical advances, clinically effective regenerative therapies including stem …

Background Diabetic retinopathy, a major complication of diabetes mellitus, is a leading
cause of sigh-loss in working age adults. Progressive loss of integrity of the retinal …

Age-related macular degeneration (AMD) is a progressive neurodegeneration disease that
causes photoreceptor demise and vision impairments. In AMD pathogenesis, the primary …

Age-related macular degeneration (AMD) is a highly prevalent form of blindness caused by
loss death of cells of the retinal pigment epithelium (RPE). Transplantation of pluripotent …

Retinal pigment epithelium (RPE) transplants rescue photoreceptors in selected animal
models of retinal degenerative disease. Early clinical studies of RPE transplants as …

Pluripotent stem cells (PSCs) are important for studying development and hold great
promise in regenerative medicine due to their ability to differentiate into various cell types. In …

Numerous studies demonstrated the ability of stem cells in general, and endogenous adult
stem cells in particular, to be a positive influence in the field of regenerative medicine …

Macular degeneration (MD) is a group of diseases characterized by irreversible and
progressive vision loss. Patients with MD suffer from severely impaired central vision …