Vascular inflammation and oxidative stress: major triggers for cardiovascular disease

S Steven, K Frenis, M Oelze, S Kalinovic… - Oxidative medicine …, 2019 - Wiley Online Library
Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …

Innate immune receptors in platelets and platelet-leukocyte interactions

PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

Cardiovascular comorbidity in rheumatic diseases

MT Nurmohamed, M Heslinga, GD Kitas - Nature Reviews …, 2015 - nature.com
Patients with rheumatoid arthritis (RA) and other inflammatory joint diseases (IJDs) have an
increased risk of premature death compared with the general population, mainly because of …

Mean platelet volume: a link between thrombosis and inflammation?

A Yuri Gasparyan, L Ayvazyan… - Current …, 2011 - ingentaconnect.com
Platelet activation is a link in the pathophysiology of diseases prone to thrombosis and
inflammation. Numerous platelet markers, including mean platelet volume (MPV), have been …

An increase in mean platelet volume from baseline is associated with mortality in patients with severe sepsis or septic shock

CH Kim, SJ Kim, MJ Lee, YE Kwon, YL Kim, KS Park… - PloS one, 2015 - journals.plos.org
Introduction Mean platelet volume (MPV) is suggested as an index of inflammation, disease
activity, and anti-inflammatory treatment efficacy in chronic inflammatory disorders; however …

Mean platelet volume as an indicator of disease severity in patients with acute pancreatitis

Y Beyazit, A Sayilir, S Torun, B Suvak, Y Yesil… - Clinics and research in …, 2012 - Elsevier
Aim Acute pancreatitis (AP) constitutes a systemic inflammatory process which is often
accompanied by thrombosis and bleeding disorders. The role of platelets in the …

Platelet function in rheumatoid arthritis: arthritic and cardiovascular implications

AY Gasparyan, A Stavropoulos-Kalinoglou… - Rheumatology …, 2011 - Springer
Patients with rheumatoid arthritis (RA) are at high risk of cardiovascular events. Platelet
biomarkers are involved in inflammation, atherosclerosis and thrombosis. Cardiovascular …

Mean platelet volume/platelet count ratio as a predictor of long-term mortality after non-ST-elevation myocardial infarction

B Azab, E Torbey, J Singh, M Akerman, G Khoueiry… - Platelets, 2011 - Taylor & Francis
Previous studies reported an association between elevated mean platelet volume (MPV)
and post-myocardial infarction mortality. This study explores the association between long …

The role of mean platelet volume as a predictor of mortality in critically ill patients: a systematic review and meta‐analysis

P Tajarernmuang, A Phrommintikul… - … care research and …, 2016 - Wiley Online Library
Background. An increase in the mean platelet volume (MPV) has been proposed as a novel
prognostic indicator in critically ill patients. Objective. We conducted a systematic review and …

Mean platelet volume and immature platelet fraction in autoimmune disorders

D Schmoeller, MM Picarelli, T Paz Munhoz… - Frontiers in …, 2017 - frontiersin.org
Mean platelet volume (MPV), measured using automated blood analysers, has been
appraised as a potential biomarker in cardiovascular disease, diabetes mellitus, and cancer …