Single-cell transcriptomic studies unveil potential nodes of the notochord gene regulatory network

LJ Negrón-Piñeiro, A Di Gregorio - Integrative and Comparative …, 2024 - academic.oup.com
Transcription factors (TFs) are DNA-binding proteins able to modulate the timing, location,
and levels of gene expression by binding to regulatory DNA regions. Therefore, the …

Cis-regulatory interfaces reveal the molecular mechanisms underlying the notochord gene regulatory network of Ciona

LJ Negrón-Piñeiro, Y Wu, S Popsuj… - Nature …, 2024 - nature.com
Tissue-specific gene expression is fundamental in development and evolution, and is
mediated by transcription factors and by the cis-regulatory regions (enhancers) that they …

Matrix metalloproteinase Nas15 regulates the lumen formation and expansion in Ciona notochord

J Bi, Y Ge, Z Wang, H Peng, B Dong - Frontiers in Ecology and …, 2024 - frontiersin.org
Lumen formation, as a key process of biological tube construction, is essential in various
physiological processes such as nutrient and waste transporting, gas exchanging, and …

[HTML][HTML] Fine-Tuned Expression of Evolutionarily Conserved Signaling Molecules in the Ciona Notochord

LJ Negrón-Piñeiro, Y Wu, R Mehta, JE Maguire… - International journal of …, 2024 - mdpi.com
The notochord is an axial structure required for the development of all chordate embryos,
from sea squirts to humans. Over the course of more than half a billion years of chordate …

[HTML][HTML] Searching for marine embryos, finding my path

A Di Gregorio - Genesis (New York, NY: 2000), 2023 - pmc.ncbi.nlm.nih.gov
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