The hand endows us with unparalleled precision and versatility in our interactions with
objects, from mundane activities such as grasping to extraordinary ones such as virtuoso …

Pluripotent stem cells show a remarkable ability to self-organize and differentiate in vitro in
three-dimensional aggregates, known as organoids or organ spheroids, and to recapitulate …

Humans possess an extraordinary capacity for cultural production, from the arts and
language to science and technology. How did the human mind—and the uniquely human …

The nervous system—in particular, the brain and its cognitive abilities—is among humans'
most distinctive and impressive attributes. How the nervous system has changed in the …

In most animals, the brain controls the body via a set of descending neurons (DNs) that
traverse the neck. DN activity activates, maintains or modulates locomotion and other …

The corticospinal tract (CST) plays a major role in cortical control of spinal cord activity. In
particular, it is the principal motor pathway for voluntary movements. Here, we discuss:(i) the …

Each of the descending pathways involved in motor control has a number of anatomical,
molecular, pharmacological, and neuroinformatic characteristics. They are differentially …

Axonal regeneration in the central nervous system (CNS) is a highly energy-demanding
process. Extrinsic insults and intrinsic restrictions lead to an energy crisis in injured axons …

What changes in neural architecture account for the emergence and expansion of dexterity
in primates? Dexterity, or skill in performing motor tasks, depends on the ability to generate …

This book presents a comprehensive account of the regions of the brain that control the
performance of skilled voluntary movements, especially the accurate and precise control of …