Pluripotent stem cells show a remarkable ability to self-organize and differentiate in vitro in three-dimensional aggregates, known as organoids or organ spheroids, and to recapitulate …
Humans possess an extraordinary capacity for cultural production, from the arts and language to science and technology. How did the human mind—and the uniquely human …
The nervous system—in particular, the brain and its cognitive abilities—is among humans' most distinctive and impressive attributes. How the nervous system has changed in the …
In most animals, the brain controls the body via a set of descending neurons (DNs) that traverse the neck. DN activity activates, maintains or modulates locomotion and other …
Q Welniarz, I Dusart, E Roze - Developmental neurobiology, 2017 - Wiley Online Library
The corticospinal tract (CST) plays a major role in cortical control of spinal cord activity. In particular, it is the principal motor pathway for voluntary movements. Here, we discuss:(i) the …
Each of the descending pathways involved in motor control has a number of anatomical, molecular, pharmacological, and neuroinformatic characteristics. They are differentially …
Axonal regeneration in the central nervous system (CNS) is a highly energy-demanding process. Extrinsic insults and intrinsic restrictions lead to an energy crisis in injured axons …
PL Strick, RP Dum, JA Rathelot - Annual Review of …, 2021 - annualreviews.org
What changes in neural architecture account for the emergence and expansion of dexterity in primates? Dexterity, or skill in performing motor tasks, depends on the ability to generate …
This book presents a comprehensive account of the regions of the brain that control the performance of skilled voluntary movements, especially the accurate and precise control of …