Cytokine-induced senescence in the tumor microenvironment and its effects on anti-tumor immune responses
M Rentschler, H Braumüller, PS Briquez, T Wieder - Cancers, 2022 - mdpi.com
Simple Summary Despite tremendous treatment efforts, cancer is still one of the leading
causes of death, with approximately 10 million deaths in 2020. In the last decade …
causes of death, with approximately 10 million deaths in 2020. In the last decade …
A paradoxical effect of interleukin-32 isoforms on cancer
S Shim, S Lee, Y Hisham, S Kim, TT Nguyen… - Frontiers in …, 2022 - frontiersin.org
IL-32 plays a contradictory role such as tumor proliferation or suppressor in cancer
development depending on the cancer type. In most cancers, it was found that the high …
development depending on the cancer type. In most cancers, it was found that the high …
Alteration of E2F2 expression in governing endothelial cell senescence
H Liu, L Chen, W Xiao, J Liu, C Long, W Zhan, C Cui… - Genes, 2022 - mdpi.com
Endothelial cell senescence has a vital implication for vascular dysfunction, leading to age-
related cardiovascular disease, especially hypertension and atherosclerosis. E2F …
related cardiovascular disease, especially hypertension and atherosclerosis. E2F …
Identification of senescence-related subtypes, establishment of a prognosis model, and characterization of a tumor microenvironment infiltration in breast cancer
Y Zhou, L Xiao, G Long, J Cao, S Liu, Y Tao… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is a malignancy with the highest incidence and mortality in women worldwide.
Senescence is a model of arrest in the cell cycle, which plays an important role in tumor …
Senescence is a model of arrest in the cell cycle, which plays an important role in tumor …
Synthesis and in vitro evaluation of benzo [b] thiophene-3-carboxylic acid 1, 1-dioxide derivatives as anticancer agents targeting the RhoA/ROCK pathway
J Liang, J Huang, J Yang, W Liang, H Li… - Journal of Enzyme …, 2024 - Taylor & Francis
Rho family GTPases regulate cellular processes and promote tumour growth and
metastasis; thus, RhoA is a potential target for tumour metastasis inhibition. However, limited …
metastasis; thus, RhoA is a potential target for tumour metastasis inhibition. However, limited …
BUB1/KIF14 complex promotes anaplastic thyroid carcinoma progression by inducing chromosome instability
T Jin, L Ding, J Chen, X Zou, T Xu… - Journal of Cellular …, 2024 - Wiley Online Library
Chromosome instability (CIN) is a common contributor driving the formation and progression
of anaplastic thyroid cancer (ATC), but its mechanism remains unclear. The BUB1 mitotic …
of anaplastic thyroid cancer (ATC), but its mechanism remains unclear. The BUB1 mitotic …
Tabula Sapiens reveals transcription factor expression, senescence effects, and sex-specific features in cell types from 28 human organs and tissues
Tabula Sapiens Consortium, SR Quake - bioRxiv, 2024 - biorxiv.org
The Tabula Sapiens is a reference human cell atlas containing single cell transcriptomic
data from more than two dozen organs and tissues. Here we report Tabula Sapiens 2.0 …
data from more than two dozen organs and tissues. Here we report Tabula Sapiens 2.0 …
[PDF][PDF] Alteration of E2F2 Expression in Governing Endothelial Cell Senescence. Genes 2022, 13, 1522
H Liu, L Chen, W Xiao, J Liu, C Long, W Zhan, C Cui… - 2022 - academia.edu
Endothelial cell senescence has a vital implication for vascular dysfunction, leading to
agerelated cardiovascular disease, especially hypertension and atherosclerosis. E2F …
agerelated cardiovascular disease, especially hypertension and atherosclerosis. E2F …
[引用][C] Cytokine-Induced Senescence in the Tumor Microenvironment and Its Effects on Anti-Tumor Immune Responses. Cancers 2022, 14, 1364
M Rentschler, H Braumüller, PS Briquez… - 2022 - s Note: MDPI stays neutral with …