As an evolutionarily conserved signalling network, the Hippo pathway plays a crucial role in
the regulation of numerous biological processes. Thus, substantial efforts have been made …

A central function of the vascular endothelium is to serve as a barrier between the blood and
the surrounding tissue of the body. At the same time, solutes and cells have to pass the …

Ferroptosis is a phospholipid peroxidation-mediated and iron-dependent cell death form,
involved in sepsis-induced organ injury and other lung diseases. Yes-associated protein 1 …

Background: The transcription factor BACH1 (BTB and CNC homology 1) suppressed
endothelial cells (ECs) proliferation and migration and impaired angiogenesis in the …

The transcription coactivator YAP plays a vital role in Hippo pathway for organ-size control
and tissue homeostasis. Recent studies have demonstrated YAP is closely related to …

Summary The Hippo/Yes-associated protein (YAP) pathway has pivotal roles in innate
immune responses against pathogens in macrophages. However, the role of YAP in …

Recognition of pathogen-associated molecular patterns (PAMPs) triggers expression of
antiviral interferons and proinflammatory cytokines, which functions as the frontier of host …

The endothelial cells (ECs) make up the inner lining of blood vessels, acting as a barrier
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …

Innate immune cells are responsible for eliminating foreign infectious agents and cellular
debris, and their ability to perceive, respond to, and integrate biochemical and mechanical …

Simple Summary Intercellular adhesion molecule 1 (ICAM-1) is a protein produced by cells
in blood vessel walls, as well as many other cell types. It localizes to the surface of these …