Sexual reproduction requires the fusion of sperm cell and oocyte during fertilization to
produce the diploid zygote. In mammals complex changes in the plasma membrane of the …

A proper dialogue between spermatozoa and the egg is essential for conception of a new
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …

Steroid hormone progesterone released by cumulus cells surrounding the egg is a potent
stimulator of human spermatozoa. It attracts spermatozoa towards the egg and helps them …

To fuse with oocytes, spermatozoa of eutherian mammals must pass through extracellular
coats, the cumulus cell layer, and the zona pellucida (ZP). It is generally believed that the …

The goal of sperm is to fertilize the oocyte. To achieve that purpose, it must acquire motility in
the epididymis and hyperactivated motility in the female reproductive tract. Motility is only …

Ion channels control the sperm ability to fertilize the egg by regulating sperm maturation in
the female reproductive tract and by triggering key sperm physiological responses required …

The identification of human sperm hyperactivated motility has potential importance in sperm
function tests, as well as in quality control assays and in reproductive toxicology …

Fertilization is defined as the process of union of two germ cells, egg and sperm, whereby
the somatic chromosome number is restored and the development of a new individual …

Fertilization is the fusion of the male and female gamete. The process involves the fusion of
an oocyte with a sperm, creating a single diploid cell, the zygote, from which a new …

Sperm–egg interaction is a carbohydrate-mediated species-specific event which initiates a
signal transduction cascade resulting in the exocytosis of sperm acrosomal contents (ie, the …