Targeted therapy has become an effective strategy of precision medicine for improving
cancer treatment. Selectivity improvement is always popular in modern oncology because of …

Nanomedicines are extensively explored for cancer therapy. By delivering drug molecules
more efficiently to pathological sites and by attenuating their accumulation in healthy organs …

Introduction Since the prostate-specific membrane antigen (PSMA) is frequently over-
expressed in prostate cancer (PCa) several PSMA-targeting molecules are under …

Despite the potential of deep learning (DL)-based methods in substituting CT-based PET
attenuation and scatter correction for CT-free PET imaging, a critical bottleneck is their …

A copper-mediated radiofluorination of aryl-and vinylboronic acids with K18F is described.
This method exhibits high functional group tolerance and is effective for the radiofluorination …

Conventional cancer chemotherapy heavily relies on the use of cytotoxic agents, which
typically do not preferentially localize at the tumor site and cause toxicity to normal organs …

We present the first direct comparative evaluation of an antibody–drug conjugate and of a
small molecule–drug conjugate for cancer therapy, using chemically defined products which …

Positron (β+) emission tomography (PET) is a powerful, noninvasive tool for the in vivo, three-
dimensional imaging of physiological structures and biochemical pathways. The continued …

Several FDA/EMA‐approved nanomedicines have demonstrated improved
pharmacokinetics and toxicity profiles compared to their conventional chemotherapeutic …

Antibody–drug conjugates (ADCs) represent a promising class of biopharmaceuticals with
the potential to localize at the tumor site and improve the therapeutic index of cytotoxic …