Immunity and inflammation in epilepsy

A Vezzani, B Lang, E Aronica - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
This review reports the available evidence on the activation of the innate and adaptive
branches of the immune system and the related inflammatory processes in epileptic …

Immune therapy in autoimmune encephalitis: a systematic review

M Nosadini, SS Mohammad… - Expert review of …, 2015 - Taylor & Francis
We have reviewed the literature of immune therapy in autoimmune encephalitis associated
with antibodies to cell surface antigens including N-methyl-D-aspartate receptor (NMDAR) …

Seizures and risk of epilepsy in autoimmune and other inflammatory encephalitis

M Spatola, J Dalmau - Current opinion in neurology, 2017 - journals.lww.com
Although seizures are frequent in all types of autoimmune encephalitis, the risk for chronic
epilepsy is dependent on the antigen: lower if located on the cell-surface, and higher if …

[HTML][HTML] Autoimmune epilepsy

KS Husari, D Dubey - Neurotherapeutics, 2019 - Elsevier
The field of autoimmune epilepsy has evolved substantially in the last few decades with
discovery of several neural autoantibodies and improved mechanistic understanding of …

Inflammatory aspects of epileptogenesis: contribution of molecular inflammatory mechanisms

F Alyu, M Dikmen - Acta neuropsychiatrica, 2017 - cambridge.org
ObjectiveEpilepsy is a chronic neurological disease characterised with seizures. The
aetiology of the most generalised epilepsies cannot be explicitly determined and the …

Epileptogenic effects of NMDAR antibodies in a passive transfer mouse model

S Wright, K Hashemi, L Stasiak, J Bartram, B Lang… - Brain, 2015 - academic.oup.com
Most patients with N-methyl D-aspartate-receptor antibody encephalitis develop seizures but
the epileptogenicity of the antibodies has not been investigated in vivo. Wireless …

LGI1 and CASPR2 neurological autoimmunity in children

AS López‐Chiriboga, C Klein, A Zekeridou… - Annals of …, 2018 - Wiley Online Library
The clinical phenotype of leucine‐rich glioma‐inactivated protein 1 (LGI1) and contactin‐
associated proteinlike 2 (CASPR2) autoimmunity is well defined in adults. Data for children …

LGI1 and CASPR2 autoimmunity in children: systematic literature review and report of a young girl with Morvan syndrome

M Nosadini, I Toldo, B Tascini, CG Bien… - Journal of …, 2019 - Elsevier
Leucine-rich glioma-inactivated protein 1 (LGI1) and contactin-associated protein-like 2
(CASPR2) neurological autoimmunity in adults has been associated with various clinical …

The recognition and treatment of autoimmune epilepsy in children

J Suleiman, RC Dale - Developmental Medicine & Child …, 2015 - Wiley Online Library
There is emerging interest in autoimmune epilepsy, which represents a small but potentially
treatable form of epilepsy. Most insights into autoimmune epilepsy derive from the recent …

Autoimmune epilepsy-novel multidisciplinary analysis, discoveries and insights

M Levite, H Goldberg - Frontiers in Immunology, 2022 - frontiersin.org
Epilepsy affects~ 50 million people. In~ 30% of patients the etiology is unknown, and~ 30%
are unresponsive to anti-epileptic drugs. Intractable epilepsy often leads to multiple seizures …