Obesity, classified as an epidemic by the WHO, is a disease that continues to grow
worldwide. Obesity results from abnormal or excessive accumulation of fat and usually leads …

The purpose of this study was to clarify the relationship among X-box-binding protein 1
unspliced, spliced (XBP1u, s), Forkhead box O1 (FoxO1) and autophagy in the auditory cells …

Monosodium glutamate (MSG) is widely used in food preparation industry and has been
consumed regularly. Previous studies had reported on effects of MSG when given at …

Endoplasmic reticulum (ER) is the cellular compartment where secreted and integral
membrane proteins are folded and matured. The accumulation of unfolded or misfolded …

AIM: To investigate the associations between miRNA-103 (miR-103) and insulin resistance
and nonalcoholic fatty liver disease (NAFLD). METHODS: Serum samples were collected …

Syzygium cumini (L.) Skeels (Myrtaceae) has been traditionally used to treat a number of
illnesses. Ethnopharmacological studies have particularly addressed antidiabetic and …

Subclinical hypothyroidism (SCH) and diabetes mellitus are closely related and often occur
together in individuals. However, the underlying mechanism of this association is still …

Overconsumption of a diet rich in fat and carbohydrates, called the Western diet, is a major
contributor to the global epidemic of cardiovascular disease. Despite previously …

Background and aims A high serum level of saturated free fatty acids (FFAs) is associated
with the development of nonalcoholic fatty liver disease (NAFLD). X-box binding protein-1 …

Abstract X box-binding protein-1 (XBP1) is a transcription factor that is essential for the
unfolded protein response (UPR) and the differentiation of plasma cells, and some findings …