Homeostasis of energy is regulated by genetic factors, food intake, and energy expenditure.
When energy input is greater than expenditure, the balance is positive, which can lead to …

This Review highlights the processing and integration performed by hindbrain nuclei,
focusing on the inputs received by nucleus tractus solitarius (NTS) neurons. These inputs …

Dopamine is an important neuromodulator that exerts widespread effects on the central
nervous system (CNS) function. Disruption in dopaminergic neurotransmission can have …

The mechanisms for controlling food intake involve mainly an interplay between gut, brain,
and adipose tissue (AT), among the major organs. Parasympathetic, sympathetic, and other …

Experiments in animals suggest that the neuropeptide oxytocin acts as an anorexigenic
signal in the central nervous control of food intake. In humans, however, research has …

Neuropeptides are a diverse class of signaling molecules in metazoans. They occur in all
animals with a nervous system and also in neuron-less placozoans. However, their origin …

There is growing evidence that oxytocin (OXT), a hypothalamic hormone well recognized for
its effects in inducing parturition and lactation, has important metabolic effects in both sexes …

The hypothalamus is a center of convergence and integration of multiple nutrient-related
signals. It can sense changes in circulating adiposity hormones, gastric hormones and …

Overeating and arrhythmic feeding promote obesity and diabetes. Glucagon-like peptide-1
receptor (GLP-1R) agonists are effective anti-obesity drugs but their use is limited by side …

The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological
processes, including parturition, lactation, cell growth, wound healing, and social behavior …