Mechanisms of toxic cardiomyopathy

P Hantson - Clinical toxicology, 2019 - Taylor & Francis
Background: Dilated cardiomyopathy is a frequent disease responsible for 40–50% of cases
of heart failure. Idiopathic cardiomyopathy is a primary disorder often related to …

A practical approach to avoiding cardiovascular adverse effects of psychoactive medications

J Brouillette, S Nattel - Canadian Journal of Cardiology, 2017 - Elsevier
Drugs that act on mental state, generally termed “psychoactive agents,” are among the most
widely used medications in medicine. Psychoactive agents can affect the cardiovascular …

[HTML][HTML] Lithium-induced bradycardia and cardiomyopathy in a patient with bipolar disorder and paranoid schizophrenia

M Khalid, W Sheikh, M Sherazi, TF Imran - Cureus, 2023 - ncbi.nlm.nih.gov
Lithium is primarily known to cause neurological and gastrointestinal side effects, however,
cardiac effects have been rarely reported. We present a unique case of lithium cardiotoxicity …

[HTML][HTML] Oral supplementation of inositols effectively recovered lithium-induced cardiac dysfunctions in mice

S L'Abbate, G Nicolini, F Forini, E Lepore… - Biomedicine & …, 2024 - Elsevier
This study investigates the effects of inositol (INO) supplementation on cardiac changes
caused by Li in mice. The study involved 4 groups of C57BL6 mice (n= 10 each):(i) mice …

Lithium interacts with cardiac remodeling: the fundamental value in the pharmacotherapy of bipolar disorder

PH Chen, TF Chao, YH Kao, YJ Chen - Progress in Neuro …, 2019 - Elsevier
Patients with bipolar disorder (BD) have an increased risk of cardiovascular morbidity and
mortality during the course of their illness. For over half a century, lithium has been the gold …

Cardiomyopathy secondary to long-term treatment with lithium: a case report and literature review

ÁSR Enríquez, AB Prados, AS Petcu - Journal of Clinical …, 2018 - journals.lww.com
DISCUSSION On the basis of available literature, QTc prolongation is associated with
multiple medications this individual received; interestingly, fluphenazine has yet to be …

Cardiac chronotropic hypo-responsiveness and atrial fibrosis in rats chronically treated with lithium

S Moradi, A Aminian, A Abdollahi, A Jazayeri… - Autonomic …, 2019 - Elsevier
Lithium is a widely used mood-stabilizing agent; however, it causes a variety of
cardiovascular side effects including sinus node dysfunction. In this study we explored the …

Cardiac Effects of Lithium Therapy: Tailoring Treatment Decisions

PK Chandrasekaran, LC Yee, TW Jun… - Malaysian Journal of …, 2021 - journals.lww.com
Lithium is invaluable in the management of bipolar disorders and treatment-resistant
depression. However, its narrow therapeutic-toxicity index warrants regular monitoring of its …

Analysis of Mediating effect of Depression on the Association Between Self-Esteem and Eating Attitude: A Study Among Female Students

P Talwar, K Pai - Malaysian Journal of Psychiatry, 2021 - journals.lww.com
Objective: Research indicates there is a link between self-esteem, depression and eating
disorders. Studies point toward depression as the intervening variable in the relationship …

Normal levels of lithium–Can it still be harmful?

S Panda, R Singh, M Gurjar… - Indian Journal of …, 2019 - journals.lww.com
Lithium (Li) is a first-line drug for bipolar disorder which has a narrow therapeutic window
(0.6–1.2 mEq/L).[1, 2] Chronic long-term use can have prolonged elimination half-life …