Gingival crevicular fluid as a source of biomarkers for periodontitis

SP Barros, R Williams, S Offenbacher… - Periodontology …, 2016 - Wiley Online Library
In evaluating the pathogenesis of periodontal diseases, the diagnostic potential of gingival
crevicular fluid has been extensively explored during the last twenty years, from initially just …

Utility of gingival crevicular fluid components for periodontal diagnosis

N Buduneli, B Bıyıkoğlu, DF Kinane - Periodontology 2000, 2024 - Wiley Online Library
Periodontal diseases are highly prevalent chronic diseases, and severe periodontitis
creates functional and esthetic problems and decreases self‐esteem for a large percentage …

Diagnostic potential and future directions of biomarkers in gingival crevicular fluid and saliva of periodontal diseases: Review of the current evidence

NA Ghallab - Archives of oral biology, 2018 - Elsevier
Objectives The holy grail of biomarker research in periodontology is to develop a high
impact diagnostics which have a significant impact on clinical decision-making, patient …

Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's

CE Toomey, WE Heywood, JR Evans, J Lachica… - Acta neuropathologica …, 2022 - Springer
Background The molecular drivers of early sporadic Parkinson's disease (PD) remain
unclear, and the presence of widespread end stage pathology in late disease masks the …

[HTML][HTML] Salivary biomarkers and proteomics: future diagnostic and clinical utilities

M Castagnola, E Scarano, GC Passali… - Acta …, 2017 - ncbi.nlm.nih.gov
Saliva testing is a non-invasive and inexpensive test that can serve as a source of
information useful for diagnosis of disease. As we enter the era of genomic technologies and …

[HTML][HTML] Beyond microbial community composition: functional activities of the oral microbiome in health and disease

AE Duran-Pinedo, J Frias-Lopez - Microbes and infection, 2015 - Elsevier
The oral microbiome plays a relevant role in the health status of the host and is a key
element in a variety of oral and non-oral diseases. Despite advances in our knowledge of …

Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy

PG Moon, JE Lee, S You, TK Kim, JH Cho, IS Kim… - …, 2011 - Wiley Online Library
To identify biomarker candidates associated with early IgA nephropathy (IgAN) and thin
basement membrane nephropathy (TBMN), the most common causes presenting isolated …

UPLC–MSE application in disease biomarker discovery: the discoveries in proteomics to metabolomics

YY Zhao, RC Lin - Chemico-biological interactions, 2014 - Elsevier
In the last decade, proteomics and metabolomics have contributed substantially to our
understanding of different diseases. Proteomics and metabolomics aims to comprehensively …

Gingival crevicular fluid and its immune mediators in the proteomic era

N Bostanci, GN Belibasakis - Periodontology 2000, 2018 - Wiley Online Library
The discovery of biomarkers for periodontal disease requires an in‐depth understanding of
the molecular basis of the initiation and progression of the disease. The gingival crevicular …

Targeted proteomics guided by label-free quantitative proteome analysis in saliva reveal transition signatures from health to periodontal disease

N Bostanci, N Selevsek, W Wolski, J Grossmann… - Molecular & Cellular …, 2018 - ASBMB
Periodontal diseases are among the most prevalent worldwide, but largely silent, chronic
diseases. They affect the tooth-supporting tissues with multiple ramifications on life quality …