The Global Expansion of Dengue: How Aedes aegypti Mosquitoes Enabled the First Pandemic Arbovirus

OJ Brady, SI Hay - Annual review of entomology, 2020 - annualreviews.org
Dengue is an emerging viral disease principally transmitted by the Aedes (Stegomyia)
aegypti mosquito. It is one of the fastest-growing global infectious diseases, with 100–400 …

Controlling vector-borne diseases by releasing modified mosquitoes

HA Flores, SL O'Neill - Nature Reviews Microbiology, 2018 - nature.com
Aedes mosquito-transmitted diseases, such as dengue, Zika and chikungunya, are
becoming major global health emergencies while old threats, such as yellow fever, are re …

[HTML][HTML] Establishment of wMel Wolbachia in Aedes aegypti mosquitoes and reduction of local dengue transmission in Cairns and surrounding locations in northern …

PA Ryan, AP Turley, G Wilson, TP Hurst… - Gates open …, 2019 - ncbi.nlm.nih.gov
Background: The wMel strain of Wolbachia has been successfully introduced into Aedes
aegypti mosquitoes and subsequently shown in laboratory studies to reduce transmission of …

Scaled deployment of Wolbachia to protect the community from dengue and other Aedes transmitted arboviruses

SL O'Neill, PA Ryan, AP Turley, G Wilson… - Gates open …, 2019 - pmc.ncbi.nlm.nih.gov
Background: A number of new technologies are under development for the control of
mosquito transmitted viruses, such as dengue, chikungunya and Zika that all require the …

Establishment of Wolbachia strain wAlbB in Malaysian populations of Aedes aegypti for dengue control

WA Nazni, AA Hoffmann, A NoorAfizah, YL Cheong… - Current biology, 2019 - cell.com
Dengue has enormous health impacts globally. A novel approach to decrease dengue
incidence involves the introduction of Wolbachia endosymbionts that block dengue virus …

Vector biology meets disease control: using basic research to fight vector-borne diseases

WR Shaw, F Catteruccia - Nature microbiology, 2019 - nature.com
Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …

Development of a confinable gene drive system in the human disease vector Aedes aegypti

M Li, T Yang, NP Kandul, M Bui, S Gamez, R Raban… - Elife, 2020 - elifesciences.org
Aedes aegypti is the principal mosquito vector for many arboviruses that increasingly infect
millions of people every year. With an escalating burden of infections and the relative failure …

Evolutionary Ecology of Wolbachia Releases for Disease Control

PA Ross, M Turelli, AA Hoffmann - Annual review of genetics, 2019 - annualreviews.org
Wolbachia is an endosymbiotic Alphaproteobacteria that can suppress insect-borne
diseases through decreasing host virus transmission (population replacement) or through …

[HTML][HTML] A decade of stability for wMel Wolbachia in natural Aedes aegypti populations

PA Ross, KL Robinson, Q Yang, AG Callahan… - PLoS …, 2022 - journals.plos.org
Mosquitoes carrying Wolbachia endosymbionts are being released in many countries for
arbovirus control. The wMel strain of Wolbachia blocks Aedes-borne virus transmission and …

Aedes spp. and Their Microbiota: A Review

F Scolari, M Casiraghi, M Bonizzoni - Frontiers in microbiology, 2019 - frontiersin.org
Aedes spp. are a major public health concern due to their ability to be efficient vectors of
dengue, Chikungunya, Zika, and other arboviruses. With limited vaccines available and no …