Neutrophils, constituting the first line of defense, perform vital functions during immune
surveillance. A key feature that assists in their prompt response to an inflammatory signal is …

Mechanical ventilation is a life-saving therapy in patients with acute respiratory distress
syndrome (ARDS). However, mechanical ventilation itself causes severe co-morbidities in …

Optical coherence tomography (OCT) is a noninvasive cross-sectional imaging technique
with micrometer resolution. The theoretical axial resolution is determined by the center …

In situ imaging of alveoli and the smaller airways with optical coherence tomography (OCT)
has significant potential in the assessment of lung disease. We present a minimally invasive …

Imaging of alveoli in situ has for the most part been infeasible due to the high resolution
required to discern individual alveoli and limited access to alveoli beneath the lung surface …

Optical coherence tomography is a rapidly maturing optical imaging technology, enabling
study of the in vivo structure of lung tissue at a scale of tens of micrometers. It has been used …

Three-dimensional optical coherence tomography (3D-OCT) was used to image the
structure and pathology of skeletal muscle tissue from the treadmill-exercised mdx mouse …

Respiratory diseases, such as pulmonary infections, are an important cause of morbidity and
mortality worldwide. Preclinical studies often require invasive techniques to evaluate the …

Intravital microscopy of the pulmonary microcirculation in research animals is of great
scientific interest for its utility in identifying regional changes in pulmonary microcirculatory …

The bronchoscope has been an invaluable tool for the pulmonologist and surgeon for over a
century. In the late 1800s, Dr Gustav Killian performed the first rigid bronchoscopy. The …