Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

Exosomes are extracellular vesicles secreted by various cells, mainly composed of lipid
bilayers without organelles. In recent years, an increasing number of researchers have …

Effective countermeasures for tendon injury remains unsatisfactory. Mesenchymal stem cell-
derived extracellular vesicles (MSC-EVs)-based therapy via regulation of Mφ-mediated …

Abstract Alzheimer's disease (AD), manifested by memory loss and a decline in cognitive
functions, is the most prevalent neurodegenerative disease accounting for 60–80% of …

An ideal drug delivery system should selectively deliver incorporated therapeutics to the
target site, escape from immune cells recognition and degradation, and act controlled …

Cellular therapy aims to replace damaged resident cells by restoring cellular and molecular
environments suitable for tissue repair and regeneration. Among several candidates …

Recently, exosomes have been extensively applied in tissue regeneration. However, their
practical applications are severely restricted by the limited exosome secretion capability of …

Due to the disconnection of surviving neural elements after spinal cord injury (SCI), such
patients had to suffer irreversible loss of motor or sensory function, and thereafter enormous …

As the organ with the highest demand for oxygen, the brain has a poor tolerance to ischemia
and hypoxia. Despite severe ischemia/hypoxia induces the occurrence and development of …

Background Intracerebral hemorrhage (ICH) is a major public health concern, and
mesenchymal stem cells (MSCs) hold great potential for treating ICH. However, the quantity …