Acute myeloid leukemia (AML) is a hematological malignancy characterized by the
accumulation of immature myeloid precursor cells. Over half of AML patients fail to achieve …

Cytarabine (Ara-C) is the first-line drug for the treatment of acute myelogenous leukemia
(AML). However, resistance eventually develops, decreasing the efficacy of Ara-C in AML …

In malignancies, cellular senescence is critical for carcinogenesis, development, and
immunological regulation. Patients with acute myeloid leukemia (AML) have not investigated …

A recent study showed that peroxiredoxins (Prxs) play an important role in the development
of pathological cardiac hypertrophy. However, the involvement of Prx5 in cardiac …

Background TSC22D domain family genes, including TSC22D1-4, play a principal role in
cancer progression. However, their expression profiles and prognostic significance in adult …

Fibroblasts are the essential cell type of skin, highly involved in the wound regeneration
process. In this study, we sought to screen out the novel genes which act important roles in …

Inhibiting a specific target in cancer cells and reducing unwanted side effects has become a
promising strategy in pancreatic cancer treatment. MAP4K4 is associated with pancreatic …

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy, characterized by
the clonal accumulation of un-orpoorly differentiated myeloid-lineage cells [1]. Rapid …

Bromodomain‐containing protein 4 (BRD4) inhibitors have been clinically developed to treat
acute myeloid leukemia (AML), but their application is limited by the possibility of drug …

2020-05-27 Assigned to GILEAD SCIENCES, INC. reassignment GILEAD SCIENCES, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …