Preparation and characterization of artesunate-nicotinamide cocrystal by solvent evaporation and slurry method

D Setyawan, R Sari, H Yusuf… - Asian Journal of …, 2013 - repository.unair.ac.id
Objective: The present study aims to prepare and characterize cocrystals of artesunate (AR)-
nicotinamide (NI) in order to improve bioavailability and efficacy of artesunate as an …

[PDF][PDF] Preparation of eutectic mixture of ketoprofen and nicotinamide for enhanced dissolution rate

E Zaini, YS Wahyuni, A Halim… - Int J Pharm Sci Rev …, 2015 - researchgate.net
To enhance the dissolution rate of ketoprofen, a poorly water-soluble drug, eutectic mixture
of ketoprofen with nicotinamide had been prepared by melting technique. The binary phase …

Peningkatan Laju Disolusi Dispersi Padat Amorf Genistein dengan PVP K-30

E Zaini, VZ Putri, MD Octavia, F Ismed - JSFK (Jurnal Sains Farmasi & …, 2017 - jsfkonline.org
Sistem dispersi padat amorf senyawa obat yang sukar larut air genistein dalam PVP K-30
dibuat dengan metode penguapan pelarut menggunakan pelarut metanol. Sistem dispersi …

[PDF][PDF] Enhancement of solubility and dissolution rate of glibenclamide by cocrystal approach with solvent drop grinding method

A Budiman, E Nurlatifah, S Amin - Int J Curr Pharm Rev Res, 2016 - researchgate.net
Solubility is one of the physical properties of active substances that affect drug absorption
after dissolved in the gastrointestinal tract. Drugs with a limited aqueous solubility show low …

Pembentukan Kokristalantarakalsium Atorvastatin dengan Isonikotinamid dan Karakterisasinya

D Gozali, HH Bahti, SN Soewandhi… - Jurnal Sains Materi …, 2018 - jurnal.batan.go.id
Abstract PEMBENTUKAN KOKRISTALANTARAKALSIUM ATORVASTATIN DENGAN
ISONIKOTINAMID DAN KARAKTERISASINYA. Penelitian ini bertujuan untuk meningkatkan …

Peningkatan laju disolusi piperine dengan pembentukan multikomponen kristal menggunakan asam nikotinat

YN Sari, E Zaini, F Ismed - JSFK (Jurnal Sains Farmasi & …, 2019 - jsfk.ffarmasi.unand.ac.id
Tujuan penelitian ini adalah untuk meningkatkan laju disolusi piperin dengan pembentukan
multikomponen kristal piperin dan asam nikotinat (1: 1) dengan metode pelarutan …

Crystal engineering of quercetin by liquid assisted grinding method

U Athiyah, PA Kusuma, T Tutik, MLAD Lestari… - Jurnal …, 2019 - journals.utm.my
Quercetin has been proposed to exhibit numerous pharmacological benefits yet suffer low
bioavailability due to the extremely low solubility. A research to study the impact of …

[PDF][PDF] Increasing solution in the drug simvastatin with solid dispersion technique using polymer Soluplus

I SOPYAN, MR RIYALDI, SR MITA, M HARIONO - Int J App Pharm, 2023 - academia.edu
Objective: Simvastatin is a bioactive compound belonging to the class II Biopharmaceutic
Classification System (BSC), which has high permeability but low solubility. The low …

[PDF][PDF] Comparison Study of Grinding and Slurry Method on Physicochemical Characteristic of Acyclovir—Succinic Acid Cocrystal

F Rahman, AN Winantari, D Setyawan… - Asian J. Pharm. Clin …, 2017 - academia.edu
Objective: This study aimed to compare the characteristics of acyclovir (ACV)-succinic acid
(SA) cocrystal with grinding and slurry method. Methods: Cocrystals were prepared using …

Solid dispersion of quercetin-PVP K-30 and its effects on the antioxidant activity

Z Gayo, H Lucida, E Zaini - Jurnal Ilmiah Farmasi, 2020 - journal.uii.ac.id
Background: Quercetin (3, 3', 4', 5, 7-pentahydroxil-flavon) is a flavone and secondary
metabolite known as flavonoid. Quercetin belongs to class II BCS that has low solubility and …