In the past decade, advances in genome sequencing have allowed researchers to uncover
the history of hybridization in diverse groups of species, including our own. Although the …

Recombination, the exchange of DNA between maternal and paternal chromosomes during
meiosis, is an essential feature of sexual reproduction in nearly all multicellular organisms …

Inferring changes in effective population size (N e) in the recent past is of special interest for
conservation of endangered species and for human history research. Current methods for …

Multiple lines of genetic and archaeological evidence suggest that there were major
demographic changes in the terminal Late Pleistocene epoch and early Holocene epoch of …

Recent work has hinted at the linkage disequilibrium (LD)-dependent architecture of human
complex traits, where SNPs with low levels of LD (LLD) have larger per-SNP heritability …

As modern humans migrated out of Africa, they encountered many new environmental
conditions, including greater temperature extremes, different pathogens and higher …

Meiotic recombination is a fundamental feature of sexually reproducing species. It is often
required for proper chromosome segregation and plays important role in adaptation and the …

Genomic studies have shown that Neanderthals interbred with modern humans, and that
non-Africans today are the products of this mixture,. The antiquity of Neanderthal gene flow …

Regulatory and coding variants are known to be enriched with associations identified by
genome-wide association studies (GWASs) of complex disease, but their contributions to …

Human-disease etiology can be better understood with phase information about diploid
sequences. We present a method for estimating haplotypes, using genotype data from …