Effect of high-fat diets on oxidative stress, cellular inflammatory response and cognitive function

BL Tan, ME Norhaizan - Nutrients, 2019 - mdpi.com
Cognitive dysfunction is linked to chronic low-grade inflammatory stress that contributes to
cell-mediated immunity in creating an oxidative environment. Food is a vitally important …

Brain metabolism alterations in type 2 diabetes: what did we learn from diet-induced diabetes models?

AM Garcia-Serrano, JMN Duarte - Frontiers in neuroscience, 2020 - frontiersin.org
Type 2 diabetes (T2D) is a metabolic disease with impact on brain function through
mechanisms that include glucose toxicity, vascular damage and blood–brain barrier (BBB) …

Neurochemical modifications in the hippocampus, cortex and hypothalamus of mice exposed to long-term high-fat diet

B Lizarbe, AF Soares, S Larsson… - Frontiers in …, 2019 - frontiersin.org
Metabolic syndrome and diabetes impact brain function and metabolism. While it is well
established that rodents exposed to diets rich in saturated fat develop brain dysfunction …

[HTML][HTML] Cognitive impairment and metabolite profile alterations in the hippocampus and cortex of male and female mice exposed to a fat and sugar-rich diet are …

AM Garcia-Serrano, AA Mohr, J Philippe… - Aging and …, 2022 - ncbi.nlm.nih.gov
Diabetes impacts on brain metabolism, structure, and function. Alterations in brain
metabolism have been observed in obesity and diabetes models induced by exposure to …

MAFLD progression contributes to altered thalamus metabolism and brain structure

S Nucera, S Ruga, A Cardamone, AR Coppoletta… - Scientific reports, 2022 - nature.com
Metabolic associated fatty liver disease (MAFLD), commonly known as non-alcoholic fatty
liver disease, represents a continuum of events characterized by excessive hepatic fat …

High fat diet impairs spermatogenesis by regulating glucose and lipid metabolism in Sertoli cells

D Luo, M Zhang, X Su, L Liu, X Zhou, X Zhang… - Life sciences, 2020 - Elsevier
Abstract Aims Sertoli cells (SCs) play an important role in the process of spermatogenesis.
SCs provide energy for germ cells (GCs) and themselves through glycolysis and fatty acid …

Exposure to maternal high-fat diet induces extensive changes in the brain of adult offspring

DJ Fernandes, S Spring, AR Roy, LR Qiu, Y Yee… - Translational …, 2021 - nature.com
Maternal environmental exposures, such as high-fat diets, diabetes and obesity, can induce
long-term effects in offspring. These effects include increased risk of neurodevelopmental …

Potential effects of resistant exercise on cognitive and muscle functions mediated by myokines in sarcopenic obese mice

G Lim, H Lee, Y Lim - Biomedicines, 2022 - mdpi.com
Recently, it has been demonstrated that in sarcopenic obesity (SO), physical activity could
improve cognitive functions. Moreover, previous studies suggested that muscle contraction …

Navigating nonalcoholic fatty liver disease (NAFLD): Exploring the roles of estrogens, pharmacological and medical interventions, and life style

Q Zuo, NH Park, JK Lee, A Santaliz-Casiano… - Steroids, 2024 - Elsevier
The pursuit of studying this subject is driven by the urgency to address the increasing global
prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) and its profound health …

Extracellular vesicles released from microglia after palmitate exposure impact brain function

GC De Paula, BI Aldana, R Battistella… - Journal of …, 2024 - Springer
Dietary patterns that include an excess of foods rich in saturated fat are associated with
brain dysfunction. Although microgliosis has been proposed to play a key role in the …