Perineuronal nets: subtle structures with large implications

H Carceller, Y Gramuntell, P Klimczak… - The …, 2023 - journals.sagepub.com
Perineuronal nets (PNNs) are specialized structures of the extracellular matrix that surround
the soma and proximal dendrites of certain neurons in the central nervous system …

The fate of interneurons, GABAA receptor sub‐types and perineuronal nets in Alzheimer's disease

AB Ali, A Islam, A Constanti - Brain Pathology, 2023 - Wiley Online Library
Alzheimer's disease (AD) is the most common neurological disease, which is associated
with gradual memory loss and correlated with synaptic hyperactivity and abnormal …

Enriched environmental exposure reduces the onset of action of the serotonin norepinephrin reuptake inhibitor venlafaxine through its effect on parvalbumin …

B Coutens, C Lejards, G Bouisset, L Verret… - Translational …, 2023 - nature.com
Mood disorders are associated with hypothalamic-pituitary-adrenal axis overactivity
resulting from a decreased inhibitory feedback exerted by the hippocampus on this brain …

[HTML][HTML] Cell-Type-Specific Expression of Leptin Receptors in the Mouse Forebrain

CR Canepa, JA Kara, CC Lee - International Journal of Molecular …, 2024 - mdpi.com
Leptin is a hormone produced by the small intestines and adipose tissue that promotes
feelings of satiety. Leptin receptors (LepRs) are highly expressed in the hypothalamus …

The impact of early life maternal deprivation on the perineuronal nets in the prefrontal cortex and hippocampus of young adult rats

A Jakovljevic, G Agatonovic, D Aleksic… - Frontiers in Cell and …, 2022 - frontiersin.org
Early life stress negatively impacts brain development and affects structure and function of
parvalbumin immunopositive (PV+) inhibitory neurons. Main regulators of PV+ interneurons …

Neuroanatomical alterations in the CNTNAP2 mouse model of autism spectrum disorder

T Gandhi, CR Canepa, TT Adeyelu, PA Adeniyi… - Brain Sciences, 2023 - mdpi.com
Autism spectrum disorder (ASD) is associated with neurodevelopmental alterations,
including atypical forebrain cellular organization. Mutations in several ASD-related genes …

Multidimensional analysis of a social behavior identifies regression and phenotypic heterogeneity in a female mouse model for Rett syndrome

M Mykins, B Bridges, A Jo, K Krishnan - Journal of Neuroscience, 2024 - Soc Neuroscience
Regression is a key feature of neurodevelopmental disorders such as autism spectrum
disorder, Fragile X syndrome, and Rett syndrome (RTT). RTT is caused by mutations in the X …

Prenatal and postnatal methamphetamine exposure alters prefrontal cortical gene expression and behavior in mice

PA Adeniyi, TT Adeyelu, A Shrestha, CC Liu… - Frontiers in Behavioral …, 2024 - frontiersin.org
Methamphetamine is a highly abused psychostimulant that substantially impacts public
health. Prenatal and postnatal methamphetamine exposure alters gene expression, brain …

[HTML][HTML] Genetic polymorphism and neuroanatomical changes in schizophrenia

MG Năstase, I Vlaicu, SC Trifu - Romanian Journal of Morphology …, 2022 - ncbi.nlm.nih.gov
The article is a review of the latest meta-analyses regarding the genetic spectrum in
schizophrenia, discussing the risks given by the disrupted-in-schizophrenia 1 (DISC1) …

Crossed connections from insular cortex to the contralateral thalamus

T Adeyelu, T Gandhi, CC Lee - Frontiers in Neural Circuits, 2021 - frontiersin.org
Sensory information in all modalities, except olfaction, is processed at the level of the
thalamus before subsequent transmission to the cerebral cortex. This incoming sensory …