The current global health threat by the novel coronavirus disease 2019 (COVID-19) requires
an urgent deployment of advanced therapeutic options available. The role of …

Photodynamic therapy is arising as a noninvasive treatment modality for cancer and other
diseases. One of the key factors to determine the therapeutic function is the efficiency of …

The clinical application of chemodynamic therapy is impeded by the insufficient intracellular
H2O2 level in tumor tissues. Herein, we developed a supramolecular nanoparticle via a …

Activation of ferroptosis, a recently described mechanism of regulated cell death,
dramatically inhibits growth of ovarian cancer cells. Given the importance of lipid metabolism …

Antibody cocktails represent a promising approach to prevent SARS-CoV-2 escape. The
determinants for selecting antibody combinations and the mechanism that antibody cocktails …

Hepatocellular carcinoma (HCC) resistant to both chemotherapy and immunotherapy is
among the deadliest malignancies. Doxorubicin widely used in transarterial chemotherapy …

Combination therapies exploit the chances for better efficacy, decreased toxicity, and
reduced development of drug resistance and owing to these advantages, have become a …

The methylthioadenosine phosphorylase (MTAP) gene is located adjacent to the cyclin-
dependent kinase inhibitor 2A (CDKN2A) tumor-suppressor gene and is co-deleted with …

Suppression of apoptosis by expression of antiapoptotic BCL2 family members is a hallmark
of acute myeloblastic leukemia (AML). Induced myeloid leukemia cell differentiation protein …

Ferroptosis is an iron-dependent, oxidative cell death, and is distinct from apoptosis,
necrosis and autophagy. In this study, we demonstrated that lysosome disrupting agent …