Three-dimensional in vitro culture models in oncology research
Cancer is a multifactorial disease that is responsible for 10 million deaths per year. The intra-
and inter-heterogeneity of malignant tumors make it difficult to develop single targeted …
and inter-heterogeneity of malignant tumors make it difficult to develop single targeted …
[HTML][HTML] Nanoparticle biodistribution coefficients: A quantitative approach for understanding the tissue distribution of nanoparticles
The objective of this manuscript is to provide quantitative insights into the tissue distribution
of nanoparticles. Published pharmacokinetics of nanoparticles in plasma, tumor and 13 …
of nanoparticles. Published pharmacokinetics of nanoparticles in plasma, tumor and 13 …
Tumor extravasation and infiltration as barriers of nanomedicine for high efficacy: The current status and transcytosis strategy
Nanotechnology-based drug delivery platforms have been explored for cancer treatments
and resulted in several nanomedicines in clinical uses and many in clinical trials. However …
and resulted in several nanomedicines in clinical uses and many in clinical trials. However …
From 2D to 3D cancer cell models—the enigmas of drug delivery research
Over the past decades, research has made impressive breakthroughs towards drug delivery
systems, resulting in a wide range of multifunctional engineered nanoparticles with …
systems, resulting in a wide range of multifunctional engineered nanoparticles with …
An update on dual targeting strategy for cancer treatment
The key issue in the treatment of solid tumors is the lack of efficient strategies for the targeted
delivery and accumulation of therapeutic cargoes in the tumor microenvironment (TME) …
delivery and accumulation of therapeutic cargoes in the tumor microenvironment (TME) …
Exploring the impact of nanoparticle stealth coatings in cancer models: from PEGylation to cell membrane-coating nanotechnology
P Graván, J Peña-Martín, JL de Andrés… - … Applied Materials & …, 2023 - ACS Publications
Nanotechnological platforms offer advantages over conventional therapeutic and diagnostic
modalities. However, the efficient biointerfacing of nanomaterials for biomedical applications …
modalities. However, the efficient biointerfacing of nanomaterials for biomedical applications …
A thermo-sensitive chitosan/pectin hydrogel for long-term tumor spheroid culture
Hydrogels represent a key element in the development of in vitro tumor models, by
mimicking the typical 3D tumor architecture in a physicochemical manner and allowing the …
mimicking the typical 3D tumor architecture in a physicochemical manner and allowing the …
DNA origami penetration in cell spheroid tissue models is enhanced by wireframe design
As DNA origami applications in biomedicine are expanding, more knowledge is needed to
assess these structures' interaction with biological systems. Here, uptake and penetration in …
assess these structures' interaction with biological systems. Here, uptake and penetration in …
Application of ultrasound combined with microbubbles for cancer therapy
D Sharma, KX Leong, GJ Czarnota - International Journal of Molecular …, 2022 - mdpi.com
At present, cancer is one of the leading causes of death worldwide. Treatment failure
remains one of the prime hurdles in cancer treatment due to the metastatic nature of cancer …
remains one of the prime hurdles in cancer treatment due to the metastatic nature of cancer …
Advances on colorectal cancer 3D models: The needed translational technology for nanomedicine screening
Colorectal cancer (CRC) is a heterogeneous and molecularly complex disease, associated
with high mortality worldwide, exposing the urgent need for novel therapeutic approaches …
with high mortality worldwide, exposing the urgent need for novel therapeutic approaches …