Aging hallmarks and the role of oxidative stress

E Maldonado, S Morales-Pison, F Urbina, A Solari - Antioxidants, 2023 - mdpi.com
Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

DNA methylation-based predictors of health: applications and statistical considerations

PD Yousefi, M Suderman, R Langdon… - Nature Reviews …, 2022 - nature.com
DNA methylation data have become a valuable source of information for biomarker
development, because, unlike static genetic risk estimates, DNA methylation varies …

Impact of Mediterranean diet on chronic non-communicable diseases and longevity

LJ Dominguez, G Di Bella, N Veronese, M Barbagallo - Nutrients, 2021 - mdpi.com
The average life expectancy of the world population has increased remarkably in the past
150 years and it is still increasing. A long life is a dream of humans since the beginning of …

[HTML][HTML] Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial

KN Fitzgerald, R Hodges, D Hanes, E Stack… - Aging (albany …, 2021 - ncbi.nlm.nih.gov
Manipulations to slow biological aging and extend healthspan are of interest given the
societal and healthcare costs of our aging population. Herein we report on a randomized …

Targeting aging mechanisms: pharmacological perspectives

A Moskalev, Z Guvatova, IDA Lopes, CW Beckett… - Trends in Endocrinology …, 2022 - cell.com
Geroprotectors slow down aging and promote healthy longevity in model animals. Although
hundreds of compounds have been shown to extend the life of laboratory model organisms …

Human age reversal: Fact or fiction?

AA Johnson, BW English, MN Shokhirev… - Aging …, 2022 - Wiley Online Library
Although chronological age correlates with various age‐related diseases and conditions, it
does not adequately reflect an individual's functional capacity, well‐being, or mortality risk …

DNA methylation-based age clocks: From age prediction to age reversion

R Noroozi, S Ghafouri-Fard, A Pisarek… - Ageing Research …, 2021 - Elsevier
Aging as an irretrievable occurrence throughout the entire life is characterized by a
progressive decline in physiological functionality and enhanced disease vulnerability …

Mediterranean diet and the hallmarks of ageing

OM Shannon, AW Ashor, F Scialo, G Saretzki… - European Journal of …, 2021 - nature.com
Ageing is a multifactorial process associated with reduced function and increased risk of
morbidity and mortality. Recently, nine cellular and molecular hallmarks of ageing have …

Mediterranean-type dietary pattern and physical activity: The winning combination to counteract the rising burden of non-communicable diseases (NCDS)

G Caprara - Nutrients, 2021 - mdpi.com
Non-communicable diseases (NCDs)(mainly cardiovascular diseases, cancers, chronic
respiratory diseases and type 2 diabetes) are the main causes of death worldwide. Their …

Nutrition strategies promoting healthy aging: From improvement of cardiovascular and brain health to prevention of age-associated diseases

M Fekete, Z Szarvas, V Fazekas-Pongor, A Feher… - Nutrients, 2022 - mdpi.com
Background: An increasing number of studies suggest that diet plays an important role in
regulating aging processes and modulates the development of the most important age …