DNA methylation data have become a valuable source of information for biomarker development, because, unlike static genetic risk estimates, DNA methylation varies …
The average life expectancy of the world population has increased remarkably in the past 150 years and it is still increasing. A long life is a dream of humans since the beginning of …
KN Fitzgerald, R Hodges, D Hanes, E Stack… - Aging (albany …, 2021 - ncbi.nlm.nih.gov
Manipulations to slow biological aging and extend healthspan are of interest given the societal and healthcare costs of our aging population. Herein we report on a randomized …
A Moskalev, Z Guvatova, IDA Lopes, CW Beckett… - Trends in Endocrinology …, 2022 - cell.com
Geroprotectors slow down aging and promote healthy longevity in model animals. Although hundreds of compounds have been shown to extend the life of laboratory model organisms …
Although chronological age correlates with various age‐related diseases and conditions, it does not adequately reflect an individual's functional capacity, well‐being, or mortality risk …
Aging as an irretrievable occurrence throughout the entire life is characterized by a progressive decline in physiological functionality and enhanced disease vulnerability …
Ageing is a multifactorial process associated with reduced function and increased risk of morbidity and mortality. Recently, nine cellular and molecular hallmarks of ageing have …
Non-communicable diseases (NCDs)(mainly cardiovascular diseases, cancers, chronic respiratory diseases and type 2 diabetes) are the main causes of death worldwide. Their …
M Fekete, Z Szarvas, V Fazekas-Pongor, A Feher… - Nutrients, 2022 - mdpi.com
Background: An increasing number of studies suggest that diet plays an important role in regulating aging processes and modulates the development of the most important age …