Radiotherapy is one of the most common countermeasures for treating a wide range of
tumors. However, the radioresistance of cancer cells is still a major limitation for …

Melanoma represents a significant clinical problem affecting a large segment of the
population with a relatively high incidence and mortality rate. Ultraviolet radiation (UVR) is …

Abstract Vanillin (4-hydroxy-3-methoxybenzaldehyde) is a known natural aromatic
flavouring agent and the major component of vanilla extracted from cured vanilla pods …

Monoaldehydes, due to natural origin and therapeutic activity, have attracted great attention
for their ability to crosslink chitosan hydrogels for biomedical applications. However, most …

Cellular senescence is a contributor to intervertebral disc (IVD) degeneration and low back
pain. Here, we found that RG-7112, a potent mouse double-minute two protein inhibitor …

Human mesenchymal stem cell (hMSC) and extracellular vesicle (EV) therapy is a promising
treatment for discogenic low back pain (LBP). Although promising, major obstacles remain to …

Accumulating evidence demonstrated that alteronol, a novel compound that has a similar
structure with paclitaxel, exerts anticancer effects against diversified tumors. However …

Curcumin is a turmeric, antioxidative compound, well-known of its anti-cancer properties.
Nowadays more and more effort is made in the field of enhancing the efficiency of the …

Inflammation and thrombosis are implicated in several non-communicable chronic
disorders, including cardiovascular diseases, diabetes, renal and neurodegenerative …

Cutaneous melanoma is a metastatic disease characterized by high resistance to treatment,
the incidence of which has alarmingly increased worldwide over the past years. A thorough …